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Oncology

NCG-M humanized mice - an excellent model for human immune reconstitution of myeloid lineages

2023-04-21

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NCG-M mice have improved reconstitution of myeloid lineage cells compared to NCG mice.

NCG-M mice supported the development of human T cells, and preliminary data showed increased B cells and NK cells as well.

NCG-M mice reconstituted with human HSC is an ideal model for preclinical in vivo efficacy evaluation of therapeutic antibodies that require human T cells and myeloid cells.


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