Coronary Heart Disease (CHD)

Coronary heart disease (CHD) is caused by coronary artery atherosclerosis and plaque rupture, leading to myocardial ischemia. Classic atherosclerotic cardiovascular disease (ASCVD) models possess significant limitations in accurately mimicking human coronary heart disease (CHD). Gempharmatech has developed several advanced CHD models that more faithfully recapitulate clinical disease presentation making these models more useful for preclinical drug evaluation.

3
Validated Models
10+
Studies Completed
2
IND Studies Completed

Advantages

Our Advantages

Industry-leading capabilities for Coronary Heart Disease (CHD)

Advanced Coronary/Plaque Rupture Models

Advanced model simulating clinical coronary heart disease and arterial plaque rupture to overcome the limitation in classic ASCVD murine models.

High Clinical Translatability

Models and studies designed to be more similar to clinical presentation and conducive for translation research.

Multi-Strain Drug Screening Platforms

Various strains to mimic human coronary heart disease for drug screening.

Model Library

CHD Models

SR-BI Mutation

Case Studies

Case Studies & Validation Data

Explore our studies demonstrating the efficacy of various therapeutic interventions.

Models

All Product Lines

Browse our comprehensive catalog of over 30,000 mouse models covering various gene families, signaling pathways, and disease models. Use advanced filters to find the perfect model for your research.