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Blogs, Webinars, Posters, and More

Blogs

TFRC-Humanized Mouse Models: A Preclinical Platform for Evaluating BBB-Penetrating Alzheimer's Therapeutics

Webinars

Selecting the Right Humanized Mouse Model for Immuno-Oncology Programs: A Practical Guide to Improving Translational Success

News

GCCL and GemPharmatech Sign MOU to Advance Global Drug Discovery and Development Services

News

GemPharmatech and Humlab Global Sign Strategic Agreement to Deliver Humanized Mouse Models for Improved Clinical Translation

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Fast‑Tracking Preclinical Discovery

Preclinical Services

Comprehensive Services, Tailored to Your Needs

GemPharmatech supports preclinical drug discovery across nine core therapeutic areas — oncology, metabolic disease, cardiovascular, autoimmune, neuroscience, infectious disease, respiratory, ophthalmology, and rare diseases. At the core of our offering is an extensive library of over 800 well-characterized drug-screening mouse and rat models, grounded in decades of in vivo pharmacology expertise.

That same expertise is brought to every client study. Our scientists work closely with your team from the outset — understanding the nuances of your program, advising on model selection, and tailoring every assessment to your specific research goals. From efficacy and toxicity to PK/PD and phenotyping, we design studies that generate the robust, reproducible data needed to make confident decisions in early development.

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Preclinical Expertise Across Every Modality

GemPharmatech’s Preclinical Service Platform delivers comprehensive,fully integrated preclinical solutions across today’s most advanced therapeutic modalities,including ADCs,TCEs,bispecifics,CAR-T,and oligonucleotides. Each modality is supported by deeply validated models, proprietary mouse strains,and scientific expertise,giving you a trusted partner capable of meeting the unique demands of your program at every stage of development.

Your Research

Scientific Support

Integrated Experimental Platforms

Running a rigorous preclinical study demands more than a well-characterized model — it requires a full suite of analytical and technical capabilities to generate complete and actionable data. GemPharmatech's integrated experimental platforms bring together molecular detection, cell engineering, pathology/imaging, PK/PD analysis, flow cytometry, in vitro assays, and behavioral analysis, reflecting our investment in building robust expertise that comprehensively supports every stage of your study.

Your Research

Scientific Support

Models to Defy Impossible

Animal Models and Services

FAD3T

Alzheimer’s disease model

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BKS-db

Obesity model

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BALB/c-Nude

Nude

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The Right Animal Model, Ready When You Need It

Finding the right in vivo model should not slow your science down. Our repository spans nearly 30,000 genetically engineered mouse strains, all maintained under SPF conditions. With an extensive off-the-shelf selection of KO and cKO models, researchers can bypass the delays of custom builds and focus on what matters most — their research. Every model is produced and maintained within AAALAC-, OLAW-, and ISO 9001-accredited facilities that meet BSL-2/ABSL-2 biosafety standards, so every model you receive meets the highest standards of quality, compliance, and biosafety.

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Why Gempharmatech

Custom Mouse Models, Built on Proven Expertise

Building a custom mouse model demands more than technical skill — it requires deep, proven experience. Having generated over 22,000 genetically engineered mouse models for our own repository, we bring an unmatched depth of expertise to every client project. That same rigor, precision, and attention to detail that built the world’s largest strain repository is applied to your custom KO, cKO, and KI models. With an annual capacity exceeding 6,000 models and a success rate above 98%, you can trust that your model will be delivered accurately, reliably, and on time.

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Who We Are

GemPharmatech

Great preclinical research requires a team that genuinely understands the science behind your program. At GemPharmatech, we are an organization of scientists working alongside fellow researchers, and that shared perspective shapes everything we do. We go beyond simply running studies — asking the right questions early, anticipating challenges before they arise, and bringing deep scientific expertise to every decision along the way. When you work with us, you gain more than a service provider. You gain a team that is as invested in the outcome of your research as you are — one that combines decades of in vivo pharmacology expertise, one of the world's most comprehensive model libraries, and fully integrated in-house capabilities to support every stage of your study. From the first conversation to the final data package, we work alongside you as true scientific partners, committed to the rigor, reproducibility, and integrity your research deserves.

Why Gempharmatech

10+
Global Headquarters&Subsidiaries
45,000+
SPF Level Facility Area
8,000+
Annual Model Creation Capacity
6,100+
SCI Articles Published

300+
IND Application Projects
300,000+
SPF grade mouse cage position
60,000+
Impact Factor

Talk to Our Team

Discuss Your Next Project

Everything we do is to provide scientists with the tools they need to advance their research. This was true when I founded GemPharmatech, when we started our knockout model collection, and true in how we move our own research and development forward.

Dr. Gao, PhD

Founder and Chairman

We are dedicated to providing our global clients with the expertise, in vivo pharmacology solutions, and premier mouse models needed to accelerate therapeutic development and improve patient lives worldwide.

Brandy Wilkinson, PhD

Chief Executive Officer

Drug developers across biotechs and pharma demand expertise and flexbility. We respect the trust our customers put in GemPharmatech as their preclinical partner, and do everything we can to become a reliable extension of their team to deliver the data and insights to move their projects forward

Jun Wang, PhD

Senior Scientific Director

Working with GemPharmatech means you gain access to an expert team of scientists, no matter your indication or modality. We continually develop new services, assays, and models to match the demands of drug discovery, aiming to become a real partner for researchers and developers

Shuxin Xu, PhD

Senior Scientific Director

Dr. Gao， PhD

Founder and Chairman

Brandy Wilkinson， PhD

Chief Executive Officer

Jun Wang， PhD

Senior Scientific Director

Shuxin Xu， PhD

Senior Scientific Director

Accelerating Innovation Through Preclinical Solutions and Genetically Engineered Animal Models