



Researchers worldwide choose GemPharmatech for extensive model availability, advanced gene-editing expertise, rigorous quality standards, and global scientific support.


Unmatched Scale, Speed & Custom Expertise
Our Knockout All Project (KOAP) provides the world's largest repository of over 22,000 KO/cKO mouse models for unmatched scale and speed, while our leading custom model generation—recognized by numerous institutions—ensures faster access to your desired model.
01

Advanced Editing Expertise
We excel in complex modifications like large-fragment knock-in and multi-gene editing, and have developed a vast library of humanized mice for advanced drug screening.
02

Global Compliance
With AAALAC, OLAW, ISO, and ICLAS accreditations and certifications, our operations are designed to meet the regulatory expectations of organizations worldwide.
03

Collaborative Partnership
From initial consultation and model selection, to logistics, delivery, and ongoing technical support, our dedicated project management team ensures a smooth, efficient partnership, allowing researchers to focus on their research.
04
Our quality assurance framework is the foundation of model reliability, encompassing genetic precision, animal health, and facility control to deliver consistent outcomes for clients around the world.
SNP Genotyping: Annual monitoring using a customized 96-SNP panel per strain to detect genetic drift and ensure stability.
Breeding Management: Pyramid breeding system (foundation, expansion, production groups) combined with cryopreservation and periodic embryo resuscitation to maintain genetic integrity.
Phenotypic QC: Systematic screening for abnormal phenotypes during breeding to ensure consistency.
Global Monitoring: Routine genetic monitoring and statistical assessment across facilities to guarantee reproducibility.

All mice are maintained under SPF or Germ-Free (GF) conditions. Regular health monitoring employs multiple methods: sentinel mice, random colony sampling, and environmental air dust (EAD) testing. Quarterly pathogen screening reports and an 18-month rolling health history are maintained for all production colonies.

Our operations are housed in state-of-the-art barrier facilities featuring HEPA filtration and meticulously controlled environments for temperature, humidity, and light cycles. Strictly enforced entry/exit protocols, regimented facility sterilization procedures and routine equipment calibration are designed to maintain biosecurity. Operations and maintenance activities are comprehensively documented to ensure traceability and compliance.

Our Certifications
AAALAC International — We are fully accredited, ensuring the highest standards of animal care and use.
OLAW Assurance — We maintain compliance with U.S. Public Health Service Policy.
ICLAS Laboratory Animal Quality Network — We are active members, connecting our quality practices to a global network of research institutions.
ISO 9001 Quality Management System Certificate — We are certified to this globally recognized standard, linking our commitment to quality with a worldwide network of continuous improvement and customer focus.
3Rs (Replacement, Reduction, and Refinement) — We are committed to these international ethical principles for the humane use of animals in research.
Access comprehensive health monitoring reports and compliance documentation for your regulatory and quality assurance needs.
Researchers can access sentinel mouse health monitoring reports featuring 18-month rolling detection results, organized by facility room. All facilities maintain rigorous SOPF standards with continuous environmental monitoring. This comprehensive testing cycle ensures continuous compliance, and the specific testing items are dynamically updated based on evolving global laboratory animal regulations, local pathogen prevalence, and specific customer requirements.
For complete transparency, we provide a definitive list of pathogenic microorganisms that are excluded from our barrier facilities. This list directly corresponds to the parameters tested in our health monitoring reports, offering a clear and auditable standard for the health status of our animals.
Comprehensive logistics solutions ensuring safe, compliant, and efficient delivery of genetically engineered models worldwide.
Expert scientific support and comprehensive intellectual property framework protecting your research and commercialization rights.
Our scientific strength is a cornerstone of our partnership model. Our team includes PhD-level scientists and seasoned technicians who provide end-to-end consultation. This support ranges from initial model design and strategy to hands-on model construction and in-depth phenotypic analysis and data interpretation.
We implement rigorous measures to safeguard your intellectual property and confidential data. All collaborations begin with a Confidential Disclosure Agreement (CDA) / Non-Disclosure Agreement (NDA). These contracts ensure that your research, model specifications, and all shared data remain strictly confidential.
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