Advancing Respiratory Disease Drug Development: A Comprehensive Mouse Platform for Translational Research

Respiratory diseases encompass infectious lung diseases, airway diseases, and parenchymal diseases. In recent years, research and development for novel therapeutics to treat these diseases have seen several exciting breakthroughs, and genetically engineered mouse models continue to stand out as an invaluable tool for evaluating those novel drugs.

GemPharmatech's expansive catalog of mouse models of respiratory disease enables assessment of drug effects from multiple perspectives, including analysis of inflammatory factors (such as TH1 and TH2 pathway cytokines), pathological alterations (e.g., inflammatory infiltration, fibrosis, tracheal wall thickening, and emphysema), and changes in lung function (FEV/FVC, FRC, Cchord).

Additionally, GemPharmatech library of over 22,000 KO (knockout) and cKO (conditional knockout) strains further supplements research into the mechanisms and genetics of respiratory diseases.

Key Highlights of this Webinar:

• An overview of major respiratory disease types including acute lung injury, Chronic Obstructive Pulmonary Disease (COPD), airway hyperresponsiveness, interstitial pulmonary fibrosis, and respiratory infections

• Introduction of GemPharmatech's mouse models of respiratory diseases 

• Case studies that illustrate how respiratory drugs are evaluated using GemPharmatech's mouse models