Preclinical Imaging and Analysis Services

Dual-Energy X-ray Absorptiometry (DEXA)

High-resolution Bone Density Assessment

High-resolution X-ray scanning enables whole-body and regional assessment of bone mineral density and changes in bone structure, supporting efficacy evaluation in osteoporosis and other bone metabolism studies.

Body Composition Analysis

Quantitative analysis of fat mass, lean tissue, and body composition helps distinguish the sources of weight change and evaluate treatment effects in metabolic disease studies.

In Vivo and Ex Vivo Imaging

DEXA supports both in vivo animal imaging and ex vivo tissue analysis, enabling researchers to correlate longitudinal phenotypic changes with tissue-level findings.

Longitudinal Studies

Noninvasive imaging enables repeated measurements in the same animals over time, supporting longitudinal analysis while potentially reducing the number of animals required.

In Vivo Optical Imaging

The in vivo optical imaging system captures and quantifies bioluminescent and fluorescent signals in living organisms, enabling real-time, non-invasive monitoring of tumor progression, metastatic spread, drug distribution, and various physiological processes in mouse models. The platform supports drug efficacy evaluation and pharmacokinetic analysis.

Ultrasound Imaging and Analysis

Cardiac Ultrasound Imaging

Cardiac Structure Assessment: High-resolution ultrasound imaging measures parameters including left ventricular internal diameter and ventricular wall thickness to assess cardiac size and structure.

Cardiac Function Assessment: Measurement of parameters including left ventricular ejection fraction and fractional shortening supports evaluation of systolic and diastolic cardiac function.

Organ Ultrasound Imaging

Liver Ultrasound: Assessment of liver size, shape, and internal echogenicity supports the detection and evaluation of liver abnormalities.

Kidney Ultrasound: Assessment of kidney size, cortical thickness, and structural abnormalities such as hydronephrosis supports evaluation of renal structure.

Blood Flow Analysis

Carotid Artery Blood Flow Detection: Coronary artery blood flow measurements support cardiovascular disease studies and evaluation of therapeutic effects.

Coronary Artery Blood Flow Detection: Echocardiography enables measurement of coronary artery blood flow to support cardiovascular disease research and evaluation of therapeutic effects.

Noninvasive Blood Pressure Measurement

Tail Artery Blood Pressure Measurement: Noninvasive tail artery measurement enables longitudinal monitoring of blood pressure in mice, including changes associated with drug intervention and disease progression.

 Ultrasound Data Analysis

The ultrasound analysis platform provides high-precision image recognition and quantitative data analysis. Measurements including organ dimensions and hemodynamic parameters support detailed assessment of cardiovascular function and organ status in mouse models.