Imaging and Analysis

Dual-Energy X-ray Absorptiometry

• High-resolution X-ray scanning for whole-body and regional bone density assessment

This technology can perform high-resolution X-ray scanning of whole-body and local bone density, accurately capturing subtle changes in bone microstructure. In the research and development of bone metabolism drugs, it can provide highly sensitive quantitative evidence for the efficacy and safety of drugs, assisting researchers in accurately evaluating the effects of drugs on bones. This helps optimize drug R & D programs and improve R & D efficiency.

• Quantitative analysis of fat, lean tissue, and body composition

This analysis method can quantitatively analyze fat, lean tissue, and body composition. In metabolic drug development, it can effectively distinguish the sources of weight change, ensuring that the drug preserves muscle while reducing fat. Through precise analysis of body composition, it can also evaluate the target selectivity of drugs, providing key data for drug R & D and facilitating the development of safer and more effective metabolic drugs.

• Suitable for In-vivo Animal and Ex-vivo Tissue Samples

This technology is suitable for both in-vivo animal experiments and ex-vivo tissue sample analysis. This enables seamless docking between pre-clinical phenotypic monitoring and ex-vivo pathological verification, ensuring data integrity from the organism to the tissue level. At all stages of drug R&D, it can provide accurate and reliable data support, helping to comprehensively evaluate the mechanism of action and effects of drugs.

• Highly Suitable for Longitudinal Studies with Repeated Measurements

It is highly suitable for longitudinal studies with repeated measurements. By using the "self-control" mode, the number of experimental animals required can be significantly reduced, lowering research costs. At the same time, it shortens the screening cycle, enabling R&D personnel to obtain experimental results more quickly and adjust R&D strategies in a timely manner, thus maximizing R&D efficiency and accelerating the drug R&D process.

In vivo Optical Imaging System

The in vivo optical imaging system captures and quantifies bioluminescent and fluorescent signals in living organisms, enabling real-time, non-invasive monitoring of tumor progression, metastatic spread, drug distribution, and various physiological processes in mouse models. This platform provides a powerful tool for drug efficacy evaluation and pharmacokinetic profiling.

Ultrasound Detection and Analysis Platform

• Cardiac Ultrasound Detection

  Cardiac Structure Assessment: Using high-resolution ultrasound imaging technology, measure indicators such as the inner diameter of the left ventricle and the thickness of the ventricular wall to evaluate whether the size and shape of the heart are normal.

  Cardiac Function Assessment: Calculate parameters such as the left ventricular ejection fraction and fractional shortening to accurately evaluate the systolic and diastolic functions of the heart.

• Organ Ultrasound Detection

Liver Ultrasound: Observe the size, shape, and internal echo of the liver to detect the presence of liver lesions.

Kidney Ultrasound: Evaluate the structure and function of the kidneys, detect the size of the kidneys, the thickness of the cortex, and the presence of abnormalities such as hydronephrosis.

Blood Flow Detection

 Carotid Artery Blood Flow Detection: Measure the blood flow velocity and blood flow volume in the carotid artery to evaluate the blood supply of the neck blood vessels.

 Coronary Artery Blood Flow Detection: Use echocardiography technology to detect the blood flow in the coronary arteries, providing an important basis for the study of coronary heart disease.

• Blood Pressure Detection

Tail Artery Blood Pressure Measurement: Adopt a non-invasive tail artery blood pressure measurement method to regularly monitor the blood pressure changes of mice and observe the blood pressure fluctuations under drug intervention or disease states.

 The ultrasound analysis system used by the platform has high - precision image recognition and data analysis functions. It can quickly and accurately analyze the detected ultrasound images and data, providing detailed research data such as organ size and hemodynamic parameters, comprehensively reflecting the cardiovascular and organ status of mice.