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Strain NO.T002289Immunodeficient

NOD/ShiLtJGpt-Rag1/Il2rg-KO
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Status
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Strain NO.
T002289
Strain Name
NOD/ShiLtJGpt-Rag1/Il2rg-KO
Background
NOD/ShiLtJGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    Rag1
  • Gene Full Name
    recombination activating 1,interleukin 2 receptor, gamma chain
  • Gene Alias
    Rag-1,CD132,[g]c,gamma(c),gc,p64
  • NCBI
  • Research Field
    immunodeficiency, Other immunodeficient strains
  • Domain Description
    1.Human-derived immune reconstitution mouse models such as BLT humanised mice, PBMC humanised mice and CD34+ humanised mice. 2.Human-derived tumour cells, tumour tissue transplantation (CDX, PDX). 3.Pharmacodynamic evaluation (small molecules, large molecules, combination drugs). 4.Human cancer models.
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