Modeling Autoimmune Diseases Utilizing Mice with Humanized Immune Systems

This webinar will explore the intricacies of reconstituting human immune cells in mice models to accurately reflect immunopathogenesis of autoimmune diseases and provide a platform for testing new therapeutic strategies for patients. GemPharmatech has developed numerous autoimmune disease models based on human immune reconstituted mice, including Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Inflammatory Bowel Disease models. These models develop human T, B, NK, and myeloid cells to enable preclinical testing of biologics against human cells or targets in vivo.   

Key Learning Objectives:

1. Reconstituting Human Immune Systems in Mice

2. Autoimmune Disease Models with Humanized Immune Systems:

    - Systemic Lupus Erythematosus (SLE)

    - Rheumatoid Arthritis (RA)

    - Inflammatory Bowel Disease (IBD)

3. Drug Efficacy Assessment