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Strain NO.T037010Gene Humanized

BALB/c-hPD1/hPDL1/hSIGLEC9
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Status
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Strain NO.
T037010
Strain Name
BALB/c-hPD1/hPDL1/hSIGLEC9
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
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model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    PDCD1
  • Gene Full Name
    programmed cell death 1,CD274 molecule,sialic acid binding Ig like lectin 9
  • Gene Alias
    PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,B7-H,B7H1,PDL1,PD-L1,hPD-L1,PDCD1L1,Sigl,Cd170,mSigle,Siglec5,Siglec9,Siglec12,Siglecl1,mSiglec-E
  • NCBI
    5133 29126 27180 18566 60533 83382
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Screening and efficacy evaluation of Siglec9 inhibitors and antibodies，such as screening of oncology therapeutics or neutralizing antibodies 2. Efficacy and safety evaluation of Siglec9-targeted drugs 3.Immune system related studies 4. Development of combinations of Siglec9-targeted drugs and PD1/PDL1 inhibitors.
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