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Strain NO.T037422Gene Humanized

BALB/c-hPD1/hCD27
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Status
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Strain NO.
T037422
Strain Name
BALB/c-hPD1/hCD27
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
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model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    PDCD1
  • Gene Full Name
    programmed cell death 1,CD27 molecule
  • Gene Alias
    CD279,PD-1,PD1,SLEB2,hPD-1,hPD-l,hSLE1,T14,S152,Tp55,TNFRSF7,S152. LPFS2
  • NCBI
    5133 939 18566 21940
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Screening and efficacy evaluation of CD27 inhibitors and antibodies，such as screening of oncology therapeutics or neutralizing antibodies 2. Efficacy and safety evaluation of CD27 inhibitors and antibodies 3. Development of combinations of CD27-targeted drugs and PD1/PDL1 inhibitors 4. Immune system related studies.
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