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Strain NO.T003361Gene Humanized

BALB/c-hCTLA4
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Status
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Strain NO.
T003361
Strain Name
BALB/c-hCTLA4
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    CTLA4
  • Gene Full Name
    cytotoxic T-lymphocyte-associated protein 4
  • Gene Alias
    Cd152,Ly-56,Ctla-4,CD,GSE,GRD4,ALPS5,CD152,CTLA-4,IDDM12,CELIAC3
  • NCBI
  • MGI
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Efficacy evaluation of human CTLA4 inhibitors such as: screening of human CTLA4 neutralizing antibodies or small molecule drugs that inhibit CTLA4 activity 2. Safety evaluation of anti-hCTLA4 antibodies 3. Immune system related studies.
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