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Strain NO.T003366Gene Humanized

B6-hTIGIT
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Status
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Strain NO.
T003366
Strain Name
B6-hTIGIT
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    TIGIT
  • Gene Full Name
    T cell immunoreceptor with Ig and ITIM domains
  • Gene Alias
    Vstm3,VSIG9,VSTM3,WUCAM
  • NCBI
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Efficacy evaluation of human TIGIT inhibitors such as: screening of human TIGIT neutralizing antibodies or small molecule drugs that inhibit TIGIT activity 2. Safety evaluation of anti-hTIGIT antibodies 3. Immune system related studies.
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