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Strain NO.T054841Gene Humanized

BALB/c-hPD1/PDL1/hTIGIT/hCD226
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Status
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Strain NO.
T054841
Strain Name
BALB/c-hPD1/PDL1/hTIGIT/hCD226
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    PDCD1
  • Gene Full Name
    CD226 molecule,CD226 antigen,T cell immunoreceptor with Ig and ITIM domains,programmed cell death 1,CD274 molecule,CD274 antigen
  • Gene Alias
    DNAM-1,DNAM1,PTA1,TLiSA1,BC051526,DNA,DNAM,DNAM-1,DNAM1,Pt,Pta1,TL,TLiSA1,VSIG9,VSTM3,WUCAM,Vst,Vstm3,PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,PD-,Pdc,PD-1,Pdc1,Ly101,B7-H
  • NCBI
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Targeted drug test (screening human CD226 neutralizing antibodies or small molecule drugs that base on human CD226 activity). 2. Evaluation of efficacy and safety of human CD226 drugs combine with human TIGIT/PD1/PDL1 inhibitor. 3. Studies on autoimmune diseases.
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