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BALB/cNj-Foxn1nu/Gpt

BALB/c-Nude|Strain NO.D000521

Spontaneous Mutation

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BASIC INFORMATION
Strain Name: BALB/cNj-Foxn1nu/Gpt
Strain Number: D000521
Official Symbol: Foxn1
Strain Strategy: D000521.BALB_c-Nude strain info.pdf
Official Full Name: forkhead box N1
Also Known As: D11Bhm185e,Fkh19,HFH-11,Hfh11,Whn,nu,nude
NCBI Number: 15218
MGI Number: 102949
Chromosome: 11
Research Areas: immunodeficiency,Other immunodeficient strains
Strain Background: [N000020] BALB/cJGpt
Modification Type: Spontaneous Mutation
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. A dynamic DNA tetrahedron framework for active targeting. Nat Protoc (2023)2. Highly efficient fabrication of functional hepatocyte spheroids by a magnetic system for the rescue of acute liver failure. Biomaterials (2023)3. DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2. Signal Transduct Target Ther (2022)4. Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-beta/SMAD3 pathway. J Hematol Oncol (2022)5. Targeting FAPα-expressing hepatic stellate cells overcomes resistance to anti-angiogenics in colorectal cancer liver metastasis models. The Journal of Clinical Investigation (2022)6. Generation of a live attenuated influenza A vaccine by proteolysis targeting. Nature Biotechnology (2022)7. Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis. J Hematol Oncol (2022)8. Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration. International Journal of Oral Science (2022)9. A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies. Molecular Cell (2021)10. Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm. Advanced Science (2021)11. NIR‐Activated Multimodal Photothermal/Chemodynamic/Magnetic Resonance Imaging Nanoplatform for Anticancer Therapy by Fe (II) Ions Doped MXenes (Fe‐Ti3C2). Small (2021)12. Polypeptide uploaded efficient nanophotosensitizers to overcome photodynamic resistance for enhanced anticancer therapy. Chemical Engineering Journal (2021)13. Cell‐Released Magnetic Vesicles Capturing Metabolic Labeled Rare Circulating Tumor Cells Based on Bioorthogonal Chemistry. Small (2021)14. MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage. Cancer Cell (2021)15. TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα. Cell Death & Differentiation (2021)16. Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells. Science advances (2021)17. Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity. Signal Transduction and Targeted Therapy (2021)18. Smart Acid‐Activatable Self‐Assembly of Black Phosphorous as Photosensitizer to Overcome Poor Tumor Retention in Photothermal Therapy. Advanced Functional Materials (2020)19. Heat stress activates YAP/TAZ to induce the heat shock transcriptome. Nature cell biology (2020)20. Integrated omics of metastatic colorectal cancer. Cancer cell (2020)21. Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma. Cell research (2020)22. Clonal mutations activate the NF-κB pathway to promote recurrence of nasopharyngeal carcinoma. Cancer research (2019)23. In Vivo Bioorthogonal Labeling of Rare-Earth Doped Nanoparticles for Improved NIR-II Tumor Imaging by Extracellular Vesicle-Mediated Targeting. Nano Research (2022)24. Rational Design of pH-Activated Upconversion Luminescent Nanoprobes for Bioimaging of Tumor Acidic Microenvironment and the Enhancement of Photothermal Therapy. Acta Biomaterialia (2022)25. FBW7-mediated ubiquitination and destruction of PD-1 protein primes sensitivity to anti-PD-1 immunotherapy in non-small cell lung cancer. J Immunother Cancer (2022)26. MAP7D2 reduces CD8(+) cytotoxic T lymphocyte infiltration through MYH9-HMGB1 axis in colorectal cancer. Molecular Therapy (2022)27. The synergistic regulation of chondrogenesis by collagen-based hydrogels and cell co-culture. Acta Biomaterialia (2022)28. Human cancer cells generate spontaneous calcium transients and intercellular waves that modulate tumor growth. Biomaterials (2022)29. TDO2+ myofibroblasts mediate immune suppression in malignant transformation of squamous cell carcinoma. Journal of Clinical Investigation (2022)30. Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation. J Immunother Cancer (2022)31. ATF4-dependent fructolysis fuels growth of glioblastoma multiforme. Nat Commun (2022)32. Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nat Commun (2022)33. Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment. Bioact Mater (2023)34. Orthogonal excitations of lanthanide nanoparticle up/down conversion emissions via switching NIR lights for in-vivo theranostics. Biomaterials (2022)35. A carbon monoxide releasing metal organic framework nanoplatform for synergistic treatment of triple-negative breast tumors. J Nanobiotechnology (2022)36. Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation. Nat Commun (2022)37. CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug. Mol Cancer (2022)38. CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin. Biomater Res (2022)39. Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs. Biomater Res (2022)40. The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling. Cell Discovery (2022)41. BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer. International Journal of Biological Sciences (2023)42. A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers. Cell Res (2023)43. Phosphomevalonate Kinase Controls beta-Catenin Signaling via the Metabolite 5-Diphosphomevalonate. Advanced Science (2023)44. Antitumor activity of aumolertinib, a third-generation EGFR tyrosine kinase inhibitor, in non-small-cell lung cancer harboring uncommon EGFR mutations. Acta Pharmaceutica Sinica B (2023)45. Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes beta-catenin palmitoylation to drive colorectal cancer progression. Cell Discovery (2023)46. METTL5 stabilizes c-Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression. Cancer Communications (2023)47. Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells. EBioMedicine (2023)48. A radiohybrid theranostics ligand labeled with fluorine-18 and lutetium-177 for fibroblast activation protein-targeted imaging and radionuclide therapy. European Journal of Nuclear Medicine and Molecular Imaging (2023)49. Modulating tumor-stromal crosstalk via a redox-responsive nanomedicine for combination tumor therapy. Journal of Controlled Release (2023)50. LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia. Journal of Hematology & Oncology (2023)51. Nano-magnetic aptamer sensor incorporating AND logic recognition-launched hybridization chain reaction for organ origin identification of circulating tumor cells. Nano Today (2023)52. CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling Pathway. Int J Biol Sci (2023)53. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1. Adv Sci (2023)54. Stimuli-responsive heparin-drug conjugates co-assembled into stable nanomedicines for cancer therapy. Acta Biomater (2023)55. The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma. SCIENCE ADVANCES (2023)56. PIBF1 regulates multiple gene expression via impeding long-range chromatin interaction to drive the malignant transformation of HPV16 integration epithelial cells. J Adv Res (2023)57. Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy. Acta Pharmaceutica Sinica B (2023)58. SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool. Nat Cell Biol (2023)59. SUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1. Cell Death Differ (2023)60. Synergism of FAK and ROS1 inhibitors in the treatment of CDH1-deficient cancers mediated by FAK-YAP signaling. International Journal of Biological Sciences (2023)61. Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy. SCI ADV (2023)62. B4GALT1 promotes immune escape by regulating the expression of PD-L1 at multiple levels in lung adenocarcinoma. J Exp Clin Cancer Res (2023)63. Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer. EBioMedicine (2023)64. NOTCH4(DeltaL12_16) sensitizes lung adenocarcinomas to EGFR-TKIs through transcriptional down-regulation of HES1. Nat Commun (2023)65. Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC. J Exp Clin Cancer Res (2023)66. Chronic stress accelerates glioblastoma progression via DRD2/ERK/beta-catenin axis and Dopamine/ERK/TH positive feedback loop. J Exp Clin Cancer Res (2023)67. Inhibition of DPAGT1 suppresses HER2 shedding and trastuzumab resistance in human breast cancer. J Clin Invest (2023)68. Targeting CD36 determines nicotine derivative NNK-induced lung adenocarcinoma carcinogenesis. iScience (2023)69. A biomimetic nanoreactor for combinational chemo/chemodynamic therapy of choriocarcinoma through synergistic apoptosis and ferroptosis strategy. Chemical Engineering Journal (2023)70. CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression. Cell Death Dis (2023)71. FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer. Cell Death Dis (2023)72. FOXP1-GINS1 axis promotes DLBCL proliferation and directs doxorubicin resistance. J Cancer (2023)73. HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway. Am J Cancer Res (2023)74. Inetetamab, a novel anti-HER2 monoclonal antibody, exhibits potent synergistic anticancer effects with cisplatin by inducing pyroptosis in lung adenocarcinoma. International Journal of Biological Sciences (2023)75. Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation. Exp Ther Med (2023)76. PC4-mediated Ku complex PARylation facilitates NHEJ-dependent DNA damage repair. J Biol Chem (2023)77. A mitochondrial EglN1-AMPKalpha axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress. EMBO J (2023)78. A safety study on ultra‑high or moderate static magnetic fields combined with platycodin D against lung cancer. Oncol Lett (2023)79. CLASRP oncogene as a novel target for colorectal cancer. Funct Integr Genomics (2023)80. DAB2IP suppresses invadopodia formation through destabilizing ALK by interacting with USP10 in breast cancer. iScience (2023)81. ELOA promotes tumor growth and metastasis by activating RBP1 in gastric cancer. Cancer Med (2023)82. Epidermal growth factor receptor regulates lineage plasticity driving transformation to small cell lung cancer. Biochem Biophys Res Commun (2023)83. In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy. Cell Death Dis (2023)84. LAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer. J Transl Med (2023)85. LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter. BMC Cancer (2023)86. Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer. Genome Med (2023)87. Single-cell RNA reveals a tumorigenic microenvironment in the interface zone of human breast tumors. Breast Cancer Res (2023)88. Thymidylate synthase promotes esophageal squamous cell carcinoma growth by relieving oxidative stress through activating nuclear factor erythroid 2-related factor 2 expression. PLoS One (2023)89. Beauvericin suppresses the proliferation and pulmonary metastasis of osteosarcoma by selectively inhibiting TGFBR2 pathway. Int J Biol Sci (2023)90. Design, Synthesis, and Biological Evaluation of a Novel [(18)F]-Labeled Arginine Derivative for Tumor Imaging. Pharmaceuticals (2023)91. Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer. Oncogene (2023)92. Ginsenoside Rh4 inhibits inflammation-related hepatocellular carcinoma progression by targeting HDAC4/IL-6/STAT3 signaling. Mol Genet Genomics (2023)93. Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis. Oncol Rep (2023)94. High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma. PeerJ (2023)95. LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter. Mol Cancer (2023)96. LINC00926 promotes progression of renal cell carcinoma via regulating miR-30a-5p/SOX4 axis and activating IFNgamma-JAK2-STAT1 pathway. Cancer Lett (2023)97. M2 Macrophage-Derived Exosomal lncRNA MIR4435-2HG Promotes Progression of Infantile Hemangiomas by Targeting HNRNPA1. Int J Nanomedicine (2023)98. Overexpression of HSPB6 inhibits osteosarcoma progress through the ERK signaling pathway. Clin Exp Med (2023)99. PHACTR1 promotes the mobility of papillary thyroid carcinoma cells by inducing F-actin formation. Heliyon (2023)100. PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma. Oncol Rep (2023)101. RACK1 facilitates breast cancer progression by competitively inhibiting the binding of beta-catenin to PSMD2 and enhancing the stability of beta-catenin. Cell Death Dis (2023)102. Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation. J Med Chem (2023)103. SECTM1 promotes the development of glioblastoma and mesenchymal transition by regulating the TGFβ1/Smad signaling pathway. International Journal of Biological Sciences (2024)104. Silencing GMPPB Inhibits the Proliferation and Invasion of GBM via Hippo/MMP3 Pathways. Int J Mol Sci (2023)105. Targeting the SOX2/CDP protein complex with a peptide suppresses the malignant progression of esophageal squamous cell carcinoma. Cell Death Discov (2023)106. TBX3 promotes the epithelial mesenchymal transition of cervical cancer by upregulating ID1. Am J Cancer Res (2023)107. The role of Her-2 in penile squamous cell carcinoma progression and cisplatin chemoresistance and potential for antibody-drug conjugate-based therapy. Eur J Cancer (2023)108. URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers. Nat Commun (2023)109. USP36 stabilizes nucleolar Snail1 to promote ribosome biogenesis and cancer cell survival upon ribotoxic stress. Nat Commun (2023)110. WDR4 promotes the progression and lymphatic metastasis of bladder cancer via transcriptional down-regulation of ARRB2. Oncogenesis (2023)111. Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression. Cell Metab (2022)112. Augmenting L3MBTL2-induced condensates suppresses tumor growth in osteosarcoma. Sci Adv (2023)113. Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer. Genome Biol (2023)114. Epidermal-dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures. NPJ Regen Med (2023)115. HILPS, a long noncoding RNA essential for global oxygen sensing in humans. Sci Adv (2023)116. Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-beta/Smad axis. Transl Oncol (2024)117. Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance. Nat Genet (2023)118. PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies. Cancer Res Commun (2023)119. SOX8 promotes tumor growth and metastasis through FZD6-dependent Wnt/beta-catenin signaling in colorectal carcinoma. Heliyon (2023)120. Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG. Cell Death Dis (2023)121. SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma. Adv Sci (2023)122. Synaptotagmin 1 Suppresses Colorectal Cancer Metastasis by Inhibiting ERK/MAPK Signaling-Mediated Tumor Cell Pseudopodial Formation and Migration. Cancers (2023)123. The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity. Cell Metab (2023)124. The m(7)G Reader NCBP2 Promotes Pancreatic Cancer Progression by Upregulating MAPK/ERK Signaling. Cancers (2023)125. Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway. World Journal of Gastroenterology (2023)126. TSTA3 overexpression promotes malignant characteristics in LUSC by regulating LAMP2-mediated autophagy and tumor microenvironment. Cancer Cell Int (2023)127. Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma. Clin Epigenetics (2023)128. ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escape. Cell Death Dis (2023)129. ASCC3 promotes the immunosuppression and progression of non-small cell lung cancer by impairing the type I interferon response via CAND1-mediated ubiquitination inhibition of STAT3. J Immunother Cancer (2023)130. Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis. DNA Cell Biol (2023)131. Essential genes analysis reveals small ribosomal subunit protein eS28 may be a prognostic factor and potential vulnerability in osteosarcoma. Journal of Bone Oncology (2024)132. Exploring the potential of carbon-coated MoSe2 nanoparticles as a photothermal therapy for ovarian cancer. Arabian Journal of Chemistry (2024)133. HOMER3 promotes non-small cell lung cancer growth and metastasis primarily through GABPB1-mediated mitochondrial metabolism. Cell Death Dis (2023)134. hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma. Mol Cancer (2023)135. Metformin Suppresses Stemness of Non-Small-Cell Lung Cancer Induced by Paclitaxel through FOXO3a. Int J Mol Sci (2023)136. PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors. Clin Cancer Res (2023)137. POU5F1 promotes the proliferation, migration, and invasion of gastric cancer cells by reducing the ubiquitination level of TRAF6. Cell Death Dis (2023)138. Predictive role of E2F6 in cancer prognosis and responses of immunotherapy. Int Immunopharmacol (2023)139. PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer. J Nanobiotechnology (2023)140. Single-particle analysis of circulating bacterial extracellular vesicles reveals their biogenesis, changes in blood and links to intestinal barrier. J Extracell Vesicles (2023)141. S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation. Burns Trauma (2023)142. Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1. Mol Cancer Ther (2023)143. Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3beta axis in non-small cell lung cancer. Cell Death Discov (2024)144. ID2 promotes tumor progression and metastasis in thyroid cancer. Endocrine (2024)145. Regulation of tumor metastasis and CD8(+) T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer. Cell Mol Biol Lett (2024)146. ALKBH5 is a prognostic factor and promotes the angiogenesis of glioblastoma. Sci Rep (2024)147. WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling. International Journal of Oral Science (2024)148. Baicalin alleviates chronic stress-induced breast cancer metastasis via directly targeting β2-adrenergic receptor. Journal of Pharmaceutical Analysis (2024)149. The miR-19a/Cylindromatosis Axis Regulates Pituitary Adenoma Bone Invasion by Promoting Osteoclast Differentiation. Cancers (2024)150. FKBP10 promotes clear cell renal cell carcinoma progression and regulates sensitivity to the HIF2alpha blockade by facilitating LDHA phosphorylation. Cell Death Dis (2024)151. Downregulation of Rab23 inhibits hepatocellular carcinoma by repressing SHH signaling pathway. Cancer Reports (2024)152. Jinfukang inhibits lung cancer metastasis by regulating T cell receptors. J Ethnopharmacol (2024)153. Enhanced Precision Therapy of Multiple Myeloma Through Engineered Biomimetic Nanoparticles with Dual Targeting. Engineering (2024)154. Ellagic acid inhibits tumor growth and potentiates the therapeutic efficacy of sorafenib in hepatocellular carcinoma. Heliyon (2024)155. Targeting DAD1 gene with CRISPR-Cas9 system transmucosally delivered by fluorinated polylysine nanoparticles for bladder cancer intravesical gene therapy. Theranostics (2024)156. Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway. Breast Cancer Res (2024)157. ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma. Int J Biol Sci (2024)158. Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain. Cell Rep (2024)159. Self-propelled assembly of nanoparticles with self-catalytic regulation for tumour-specific imaging and therapy. Nat Commun (2024)160. Proteomic analysis reveals LRPAP1 as a key player in the micropapillary pattern metastasis of lung adenocarcinoma. Heliyon (2024)161. SECTM1 promotes the development of glioblastoma and mesenchymal transition by regulating the TGFbeta1/Smad signaling pathway. Int J Biol Sci (2024)162. MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning. Cell Biosci (2024)163. CYB561 promotes HER2+ breast cancer proliferation by inhibiting H2AFY degradation. Cell Death Discov (2024)164. Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression. Cell Commun Signal (2024)165. Radiotherapy-Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth. Advanced Science (2024)166. Synergism of non-thermal plasma and low concentration RSL3 triggers ferroptosis via promoting xCT lysosomal degradation through ROS/AMPK/mTOR axis in lung cancer cells. Cell Commun Signal (2024)167. Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer. J Cell Mol Med (2024)168. Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker. Transl Oncol (2024)169. Gastric cancer secreted miR-214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells. Oncol Res (2024)170. ELF4 contributes to esophageal squamous cell carcinoma growth and metastasis by augmenting cancer stemness via FUT9. ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2023)171. SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway. Cancer Cell Int (2024)172. Vasorin exocytosed from glioma cells facilitates angiogenesis via VEGFR2 AKT signaling pathway. Molecular Cancer Research (2024)173. Urocortin-1 promotes colorectal cancer cell migration and proliferation and inhibits apoptosis via inhibition of the p53 signaling pathway. J Cancer Res Clin Oncol (2024)174. Transmembrane protein 176B regulates amino acid metabolism through the PI3K-Akt-mTOR signaling pathway and promotes gastric cancer progression. Cancer Cell Int (2024)175. Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1. J Ovarian Res (2024)176. Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer. Signal Transduct Target Ther (2024)177. Abnormal upregulation of NUBP2 contributes to cancer progression in colorectal cancer. Mol Cell Biochem (2024)178. Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer. Cancer Lett (2024)179. PELI1: key players in the oncogenic characteristics of pancreatic Cancer. J Exp Clin Cancer Res (2024)180. NSUN2 promotes colorectal cancer progression by enhancing SKIL mRNA stabilization. Clin Transl Med (2024)181. Membrane-associated RING-CH 7 inhibits stem-like capacities of bladder cancer cells by interacting with nucleotide-binding oligomerization domain containing 1. Cell Biosci (2024)182. Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway. Sci Rep (2024)183. FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation. Cell Death Discov (2024)184. FTO-mediated autophagy inhibition promotes non-small cell lung cancer progression by reducing the stability of SESN2 mRNA. Heliyon (2024)185. GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism. iScience (2024)186. Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair. Heliyon (2024)187. BZW2 promotes malignant progression in lung adenocarcinoma through enhancing the ubiquitination and degradation of GSK3beta. Cell Death Discov (2024)188. Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys. Biopharm Drug Dispos (2024)189. Accumulation of TOX high mobility group box family member 3 promotes the oncogenesis and development of hepatocellular carcinoma through the MAPK signaling pathway. MedComm (2024)190. Self-Assembled DNA Composite-Engineered Mesenchymal Stem Cells for Improved Skin-Wound Repair. Small (2024)191. TNF-alpha-Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy-Related Protein VCP. Adv Sci (2024)192. Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma. Cell Biol Toxicol (2024)193. Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis. Acta Pharm Sin B (2024)194. Anticancer potential of grifolin in lung cancer treatment through PI3K/AKT pathway inhibition. Heliyon (2024)195. APLN promotes the proliferation, migration, and glycolysis of cervical cancer through the PI3K/AKT/mTOR pathway. Arch Biochem Biophys (2024)196. Augmented ERO1alpha upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11. J Exp Clin Cancer Res (2024)197. Cancer-associated fibroblasts promote enzalutamide resistance and PD-L1 expression in prostate cancer through CCL5-CCR5 paracrine axis. iScience (2024)198. DMC-siERCC2 hybrid nanoparticle enhances TRAIL sensitivity by inducing cell cycle arrest for glioblastoma treatment. Biomed Pharmacother (2024)199. C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer. Cell Death Differ (2023)200. Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.. AMERICAN SOCIETY FOR MICROBIOLOGY (2024)201. DNMT1/miR-152-3p/SOS1 signaling axis promotes self-renewal and tumor growth of cancer stem-like cells derived from non-small cell lung cancer. Clin Epigenetics (2024)202. Frequent loss of FAM126A expression in colorectal cancer results in selective FAM126B dependency. iScience (2024)203. The pan-RAF-MEK non degrading molecular glue NST-628 is a potent and brain penetrant inhibitor of the RAS-MAPK pathway with activity across diverse RAS-and RAF-driven cancers. Cancer Discovery (2024)204. Tyrosine hydroxylase inhibits HCC progression by downregulating TGFbeta/Smad signaling. Eur J Med Res (2024)205. 20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3. Journal of Ginseng Research (2024)206. Agaricus blazei murrill and Enteromorpha prolifera-derived polysaccharides gain therapeutic effects on esophageal squamous cell carcinoma. Journal of Functional Foods (2024)207. Autocrine and Paracrine Effects of MDK Promote Lymph Node Metastasis of Cervical Squamous Cell Carcinoma. iScience (2024)208. Bmi1 facilitates the progression of cholangiocarcinoma by inhibiting Foxn2 expression dependent on a histone H2A ubiquitination manner. Cancer Lett (2024)209. BHLHE41 inhibits bladder cancer progression via regulation of PYCR1 stability and thus inactivating PI3K/AKT signaling pathway. Eur J Med Res (2024)210. Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer. J Biol Chem (2024)211. CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis. J Transl Med (2024)212. Cyclin-dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration-resistant prostate cancer. Clin Transl Med (2024)213. Deprivation of methionine inhibits osteosarcoma growth and metastasis via C1orf112-mediated regulation of mitochondrial functions. Cell Death Dis (2024)214. Development of a Specific Aptamer-Modified Nano-System to Treat Esophageal Squamous Cell Carcinoma. Adv Sci (2024)215. Enhancing antitumor efficacy of oncolytic virus M1 via albendazole-sustained CD8(+) T cell activation. MOL THER-ONCOLYTICS (2024)216. Ethanol Extracted from Radix of Actinidia Chinensis Inhibits Human Colon Tumor Through Inhibiting Notch-signaling Pathway. J Cancer (2021)217. Energy stress-induced circDDX21 promotes glycolysis and facilitates hepatocellular carcinogenesis. Cell Death Dis (2024)218. Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment. Cancer Immunol Immunother (2024)219. Ferritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer. Nat Commun (2024)220. LARP4B promotes hepatocellular carcinoma progression and impairs sorafenib efficacy by activating SPINK1-mediated EGFR pathway. Cell Death Discov (2024)221. Onvansertib in Combination with FOLFIRI and Bevacizumab in Second-Line Treatment of KRAS-Mutant Metastatic Colorectal Cancer: A Phase Ib Clinical Study. Clin Cancer Res (2024)222. O-GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression. ACS Central Science (2024)223. NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis. Cell Death Discov (2024)224. PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma. J Exp Clin Cancer Res (2024)225. Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis. Cell Mol Life Sci (2022)226. Ternary heterostructure-driven photoinduced electron-hole separation enhanced oxidative stress for triple-negative breast cancer therapy. J Nanobiotechnology (2024)227. The therapeutic effect and targets of herba Sarcandrae on breast cancer and the construction of a prognostic signature consisting of inflammation-related genes. Heliyon (2024)228. Upregulation of LHPP by saRNA inhibited hepatocellular cancer cell proliferation and xenograft tumor growth. PLoS One (2024)229. Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer. Nat Commun (2024)230. Single-Cell Chromatin Accessibility Analysis Reveals Subgroup-Specific TF-NTR Regulatory Circuits in Medulloblastoma. Adv Sci (2024)231. Cadherin 17 Nanobody-Mediated Near-Infrared-II Fluorescence Imaging-Guided Surgery and Immunotoxin Delivery for Colorectal Cancer. Biomater Res (2024)232. ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-beta signaling. Transl Oncol (2024)233. Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis. Pharmacol Res (2024)234. NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression. Cell Commun Signal (2024)235. OTUB1 Promotes Glioblastoma Growth by Inhibiting the JAK2/STAT1 Signaling Pathway. Journal of Cancer (2024)236. Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma. J Nanobiotechnology (2024)237. Can thymosin beta 10 function both as a non-invasive biomarker and chemotherapeutic target in human colorectal cancer?. Transl Oncol (2024)238. Genomic profiling of a multi-lineage and multi-passage patient-derived xenograft biobank reflects heterogeneity of ovarian cancer. Cell Rep Med (2024)239. Deacetylation of GLUD1 maintains the survival of lung adenocarcinoma cells under glucose starvation by inhibiting autophagic cell death. Cell Insight (2024)240. Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts. iScience (2024)241. Identification of TEFM as a potential therapeutic target for LUAD treatment. J Transl Med (2024)242. Identification of SLC7A11-AS1/SLC7A11 pair as a ferroptosis-related therapeutic target for hepatocellular carcinoma. J Cell Mol Med (2024)243. IKIP downregulates THBS1/FAK signaling to suppress migration and invasion by glioblastoma cells. Oncol Res (2024)244. lncRNA-WAL promotes triple-negative breast cancer aggression by inducing β-catenin nuclear translocation.. Mol Cancer Res (2024)245. Intravesical cascade delivery of active monoterpene coumarin for bladder cancer therapy. Materials Advances (2024)246. NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer. Mol Cancer (2024)247. Peptidyl-prolyl isomerase F as a prognostic biomarker associated with immune infiltrates and mitophagy in lung adenocarcinoma. Transl Lung Cancer Res (2024)248. Positive feedback loop of c-myc/XTP6/NDH2/NF-kappaB to promote malignant progression in glioblastoma. J Exp Clin Cancer Res (2024)249. Nuclear translocation of ISG15 regulated by PPP2R2B inhibits cisplatin resistance of bladder cancer. Cell Mol Life Sci (2024)250. Phase separation of RNF214 promotes the progression of hepatocellular carcinoma. Cell Death Dis (2024)251. The recruitment of CD8(+) T cells through YBX1 stabilization abrogates tumor intrinsic oncogenic role of MIR155HG in lung adenocarcinoma. Cell Death Discov (2024)252. NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression. Cell Death Dis (2024)253. Directed differentiation of pancreatic delta cells from human pluripotent stem cells. Nat Commun (2024)254. The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers. Cancer Discov (2024)255. Zinc finger protein 180 induces an apoptotic phenotype by activating METTL14 transcriptional activity in colorectal cancer. Oncol Rep (2024)256. Engineered extracellular vesicles for targeted reprogramming of cancer-associated fibroblasts to potentiate therapy of pancreatic cancer. Signal Transduct Target Ther (2024)257. Suppression of pathological neovascularization by anti-Flt1 peptide functionalized DNA tetrahedron. Chemical Engineering Journal (2024)258. A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression. Mol Cancer (2024)259. Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE(2) production. Cell Rep (2024)260. Synthetic lethality of combined ULK1 defection and p53 restoration induce pyroptosis by directly upregulating GSDME transcription and cleavage activation through ROS/NLRP3 signaling. J Exp Clin Cancer Res (2024)261. USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer. Cell Death & Disease (2024)262. Single‐Cell Chromatin Accessibility Analysis Reveals Subgroup‐Specific TF‐NTR Regulatory Circuits in Medulloblastoma. Advanced Science (2024)263. Bioorthogonal Diels-Alder Click Chemistry-Based Pretargeted PET Imaging Strategy for Monitoring Programmed Death-Ligand 1 Expression. ACS Omega (2024)264. RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression. Int J Biol Sci (2024)265. Baicalin reduces chronic stress-induced breast cancer metastasis via directly targeting beta2-adrenergic receptor. Journal of Pharmaceutical Analysis (2024)266. Polydopamine-Based Targeted Nanosystem for Chemo/Photothermal Therapy of Retinoblastoma in a Mouse Orthotopic Model. Int J Nanomedicine (2024)267. DNA self-assembly-mediated high drug-antibody ratio ADC platform for targeted tumor therapy and imaging. Nano Today (2024)268. Vasorin (VASN) overexpression promotes pulmonary metastasis and resistance to adjuvant chemotherapy in patients with locally advanced rectal cancer. J Transl Med (2024)269. Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy. Theranostics (2024)270. SelK promotes glioblastoma cell proliferation by inhibiting beta-TrCP1 mediated ubiquitin-dependent degradation of CDK4. J Exp Clin Cancer Res (2024)271. HDAC1 and FOXK1 mediate EGFR-TKI resistance of non-small cell lung cancer through miR-33a silencing. J Transl Med (2024)272. Fibrillarin reprograms glucose metabolism by driving the enhancer-mediated transcription of PFKFB4 in liver cancer. Cancer Lett (2024)273. Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer. Nature Cancer (2024)274. Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy. J Nanobiotechnology (2024)275. Selenium-Doped Nanoheterojunctions for Highly Efficient Cancer Radiosensitization. Advanced Science (2024)276. Three-in-One: Molecular Engineering of D-A-pi-A Featured Type I and Type II Near-Infrared AIE Photosensitizers for Efficient Photodynamic Cancer Therapy and Bacteria Killing. Small (2024)277. Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway. Mol Oncol (2024)278. ETHE1 dampens colorectal cancer angiogenesis by promoting TC45 Dephosphorylation of STAT3 to inhibit VEGF-A expression. Cell Death Dis (2024)279. Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1. Cell Death Dis (2024)280. Therapeutic targeting ERRgamma suppresses metastasis via extracellular matrix remodeling in small cell lung cancer. EMBO Mol Med (2024)281. HDAC2 promotes autophagy-associated HCC malignant progression by transcriptionally activating LAPTM4B. Cell Death Dis (2024)282. PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stress. Cell Mol Biol Lett (2024)283. SVIP reduces IGFBP-2 expression and inhibits glioblastoma progression via stabilizing PTEN. Cell Death Discov (2024)284. LncRNA HOXB-AS3 promotes proliferation, migration, and invasion of gallbladder cancer cells by activating the MEK/ERK pathway. Heliyon (2024)285. UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis. Cell Death Discov (2024)286. The role of BUD31 in clear cell renal cell carcinoma: prognostic significance, alternative splicing, and tumor immune environment. Clin Exp Med (2024)287. MVP enhances FGF21-induced ferroptosis in hepatocellular carcinoma by increasing lipid peroxidation through regulation of NOX4. Clinical and Translational Science (2024)288. MANF facilitates breast cancer cell survival under glucose-starvation conditions via PRKN-mediated mitophagy regulation. Autophagy (2024)289. Engineered exosomes transporting the lncRNA, SVIL-AS1, inhibit the progression of lung cancer via targeting miR-21-5p. Am J Cancer Res (2024)290. S-Doped Hollow Multi-Metallic Prussian Blue Analogue (PBA) Nanoplatform for Enhanced Anticancer for Cervical Cancer. International Journal of Nanomedicine (2024)291. Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation. Free Radic Biol Med (2024)292. METTL3 Inhibition Suppresses Cell Growth and Survival in Colorectal Cancer via ASNS Downregulation. J Cancer (2024)293. Cold atmospheric plasma enhances SLC7A11-mediated ferroptosis in non-small cell lung cancer by regulating PCAF mediated HOXB9 acetylation. Redox Biol (2024)294. Identifying and validating the roles of the cuproptosis-related gene DKC1 in cancer with a focus on esophageal carcinoma. J Cancer Res Clin Oncol (2024)295. FNIP1 suppresses colorectal cancer progression through inhibiting STAT3 phosphorylation and nuclear translocation. iScience (2024)296. Core-Shell Interface Engineering Strategies for Modulating Energy Transfer in Rare Earth-Doped Nanoparticles. Nanomaterials (2024)297. HOXA9 promotes proliferation, metastasis and prevents apoptosis in hepatocellular carcinoma. Journal of Cancer Research and Clinical Oncology (2024)298. Hypoxia-induced BAP1 enhances erastin-induced ferroptosis in nasopharyngeal carcinoma by stabilizing H2A. Cancer Cell International (2024)299. RUNX1-MUC13 Interaction Activates Wnt/β-Catenin Signaling Implications for Colorectal Cancer Metastasis. International Journal of Biological Sciences (2024)300. The microprotein HDSP promotes gastric cancer progression through activating the MECOM-SPINK1-EGFR signaling axis. Nature Communications (2024)301. Prohibitin 2 orchestrates long noncoding RNA and gene transcription to accelerate tumorigenesis. Nature Communications (2024)302. FHL2 activates β-catenin/Wnt signaling by complexing with APC and TRIM63 in lung adenocarcinoma. Translational Oncology (2024)303. DUS4L suppresses invasion and metastasis in LUAD via modulation of PI3K/AKT and ERK/MAPK signaling through GRB2. International Immunopharmacology (2024)304. NEDD9 is transcriptionally regulated by HDAC4 and promotes breast cancer metastasis and macrophage M2 polarization via the FAK/NF-κB signaling pathway. Neoplasia (2024)305. Anlotinib reverses osimertinib resistance via inhibiting epithelial-to-mesenchymal transition and angiogenesis in non-small cell lung cancer. The Journal of Biomedical Research (2024)306. SCAMP1 silencing inhibits proliferation by attenuating multiple pro-survival signaling pathways in gastric cancer. Journal of Cancer (2024)307. CLK3 promotes tumor proliferation by activating MYC signaling. Cell Division (2024)308. Therapeutic targeting ERRγ suppresses metastasis via extracellular matrix remodeling in small cell lung cancer. EMBO Molecular Medicine (2024)309. DDR1 Drives Malignant Progression of Gastric Cancer by Suppressing HIF‐1α Ubiquitination and Degradation. Advanced Science (2024)310. CircSP3 encodes SP3-461aa to promote ccRCC progression via stabilizing MYH9 and activating the PI3K-Akt signaling pathway. Journal of Cancer (2024)311. Curcumin blunts epithelial-mesenchymal transition to alleviate invasion and metastasis of prostate cancer through the JARID1D demethylation. Cancer Cell International (2024)312. Targeting GPX4-mediated ferroptosis protection sensitizes BRCA1-deficient cancer cells to PARP inhibitors. Redox Biology (2024)313. Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model. International Journal of Nanomedicine (2024)314. Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production. Cell Death & Disease (2024)315. PBA2, a novel inhibitor of the β-catenin/CBP pathway, eradicates chronic myeloid leukemia including BCR-ABL T315I mutation. Molecular Cancer (2024)316. MYO3B promotes cancer progression in endometrial cancer by mediating the calcium ion-RhoA/ROCK1 signaling pathway. Journal of Cancer Research and Clinical Oncology (2024)317. Lanthanum-based dendritic mesoporous nanoplatform for tumor microenvironment activating synergistic anti-glioma efficacy. Materials Today Bio (2024)318. PIM1 kinase promotes EMT-associated osimertinib resistance via regulating GSK3β signaling pathway in EGFR-mutant non-small cell lung cancer. Cell Death & Disease (2024)319. Chlorogenic acid exhibits antitumor effect in patient-derived xenograft models and hydrogel-embedded tissue culture drug susceptibility test of tongue cancer. Heliyon (2024)320. LMP1 enhances aerobic glycolysis in natural killer/T cell lymphoma. Cell Death Dis (2024)321. ACSL6-activated IL-18R1–NF-κB promotes IL-18–mediated tumor immune evasion and tumor progression.. Science Advances (2024)322. Enhanced tumor targeting and penetration of fluorophores via iRGD peptide conjugation: a strategy for the precision targeting of lung cancer. Translational Lung Cancer Research (2024)323. METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma. Journal of Hematology & Oncology (2024)324. DB-1314, a novel DLL3-targeting ADC with DNA topoisomerase I inhibitor, exhibits promising safety profile and therapeutic efficacy in preclinical small cell lung cancer models. J Transl Med (2024)325. DAP3 promotes mitochondrial activity and tumour progression in hepatocellular carcinoma by regulating MT-ND5 expression. Cell Death Dis (2024)326. Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC. J Adv Res (2024)327. Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity. Advanced Science (2024)328. Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity. Cell Reports (2024)329. FABP4-mediated lipid metabolism promotes TNBC progression and breast cancer stem cell activity. Cancer Letters (2024)330. Peptidylprolyl isomerase A guides SENP5/GAU1 DNA-lncRNA triplex generation for driving tumorigenesis. Nat Commun (2024)331. USP7 depletion potentiates HIF2α degradation and inhibits clear cell renal cell carcinoma progression. Cell Death Dis (2024)332. Preclinical evaluation and first-in-human study of [18F]AlF-FAP-NUR for PET imaging cancer-associated fibroblasts. EJNMMI Res (2024)333. Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci (2024)334. CircTSN promotes the proliferation and metastasis of gastric cancer through the miR-1825/SLC38A2 signaling axis. Discover Oncology (2024)335. Functional Assessments of Gynecologic Cancer Models Highlight Differences Between Single-Node Inhibitors of the PI3K/AKT/mTOR Pathway and a Pan-PI3K/mTOR Inhibitor, Gedatolisib. Cancers (Basel) (2024)336. CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation. Cell Death Dis (2024)337. RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial–mesenchymal transition. Cancer Metab (2024)338. ADAMTS4 exacerbates lung cancer progression via regulating c-Myc protein stability and activating MAPK signaling pathway. Biol Direct (2024)339. EIF4A3-mediated oncogenic circRNA hsa_circ_0001165 advances esophageal squamous cell carcinoma progression through the miR-381-3p/TNS3 pathway. Cell Biol Toxicol (2024)340. Oncolytic activity of a coxsackievirus B3 strain in patient-derived cervical squamous cell carcinoma organoids and synergistic effect with paclitaxel. Virol J (2024)341. Hypoxic glioma-derived exosomal miR-25-3p promotes macrophage M2 polarization by activating the PI3K-AKT-mTOR signaling pathway. J Nanobiotechnology (2024)342. Delta‐Like Homolog 2 Facilitates Malignancy of Hepatocellular Carcinoma via Activating EGFR/PKM2 Signaling Pathway. Mol Carcinog (2024)343. N6‐methyladenosine reader YTHDF3‐mediated zinc finger protein 41 inhibits hepatocellular carcinoma progression by transcriptional repression of Snail. MedComm (2024)344. Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway. Ann Med (2024)345. Evaluation of Double Self-Immolative Linker-Based Antibody–Drug Conjugate FDA022-BB05 with Enhanced Therapeutic Potential. J Med Chem (2024)346. NSUN5 promotes tumorigenic phenotypes through the WNT signaling pathway and immunosuppression of CD8+ T cells in gastric cancer. Cell Signal (2024)347. The lncRNA TPTEP1 suppresses PI3K/AKT signalling and inhibits ovarian cancer progression by interacting with PTBP1. J Cell Mol Med (2024)348. Serinc2 Drives the Progression of Cervical Cancer Through Regulating Myc Pathway. Cancer Med (2024)349. PLOD1 promote proliferation and migration with glycolysis via the Wnt/β-catenin pathway in THCA. Genomics (2024)350. Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer. Cell Death Differ (2024)351. Fangchinoline suppresses hepatocellular carcinoma by regulating ROS accumulation via the TRIM7/Nrf2 signaling pathway. Phytomedicine (2024)352. Growth differentiation factor 7 alleviates the proliferation and metastasis of hepatocellular carcinoma. Liver Research (2024)353. m6A RNA methyltransferase METTL16 induces Cr (VI) carcinogenesis and lung cancer development through glutamine biosynthesis and GLUL expression. J Hazard Mater (2024)354. HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2. Cell Death Differ (2024)355. Flurbiprofen axetil is involved in basal‐like breast cancer metastasis via suppressing the MEK/ERK signaling pathway. Cell Biol Int (2024)356. Androgen Receptor Mediates Dopamine Agonist Resistance by Regulating Intracellular reactive oxygen species (ROS) in Prolactin-secreting Pituitary Adenoma. Antioxid Redox Signal (2024)357. MDM4 inhibits ferroptosis in p53 mutant colon cancer via regulating TRIM21/GPX4 expression. Cell Death Dis (2024)358. PTBP1 crotonylation promotes colorectal cancer progression through alternative splicing-mediated upregulation of the PKM2 gene. J Transl Med (2024)359. NAALADL2-AS2 functions as a competing endogenous RNA to regulate apoptosis and drug resistance in DLBCL. Cancer Biol Ther (2024)360. Targeting METTL3 as a checkpoint to enhance T cells for tumour immunotherapy. Clinical and Translational Medicine (2024)361. ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma. Cell Rep (2024)362. Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes. EMBO J (2024)363. HCP5 Derived Novel Microprotein Triggers Progression of Gastric Cancer through Regulating Ferroptosis. Adv Sci (Weinh) (2024)364. Establishment and drug resistance characterization of paired organoids using human primary colorectal cancer and matched tumor deposit specimens. Hum Cell (2024)365. IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth. Cell Rep (2024)366. A machine learning-based immune response signature to facilitate prognosis prediction in patients with endometrial cancer. Scientific Reports (2024)367. CAPE activates AMPK and Foxo3 signaling to induce growth inhibition and ferroptosis in triple-negative breast cancer. PLoS One (2024)368. Wearable photobiomodulation halts thyroid cancer growth by leveraging thyroid photosensitivity. Bioengineering & Translational Medicine (2024)369. SLC25A21 correlates with the prognosis of adult acute myeloid leukemia through inhibiting the growth of leukemia cells via downregulating CXCL8. Cell Death Dis (2024)370. Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma. Cancer Cell Int (2024)371. TYMS Enhances Colorectal Cell Antioxidant Capacity Via the KEAP1-NRF2 Pathway to Resist Ferroptosis. J Cancer (2024)372. Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E3. Cell Death Discov (2024)373. FTO Facilitates Cervical Cancer Malignancy Through Inducing m6A‐Demethylation of PIK3R3 mRNA. Cancer Medicine (2024)374. Susceptibility of Mitophagy‐Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation. Adv Sci (Weinh) (2024)375. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther (2024)376. Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma. Transl Oncol (2024)377. UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation. Transl Oncol (2024)378. Multi-omics analysis reveals the interplay between intratumoral bacteria and glioma. mSystems (2024)379. FDA-Approved Hydrogel-Mediated In Situ Sonodynamic and Chemotherapeutic Therapy for Pancreatic Cancer. Pharmaceuticals (2024)380. Magnetic-Powered Spora Lygodii Microrobots Loaded with Doxorubicin for Active and Targeted Therapy of Bladder Cancer. Drug Design Development and Therapy (2024)381. Targeting RBM39 suppresses tumor growth and sensitizes osteosarcoma cells to cisplatin. Oncogene (2024)382. 4′-Demethylpodophyllotoxin functions as a mechanism-driven therapy by targeting the PI3K-AKT pathway in Colorectal cancer. Transl Oncol (2024)383. Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice. Nat Commun (2024)384. Dynamic Detection of the E3-PROTAC-Target Protein Ternary Complex In Vitro and In Vivo via Bimolecular Fluorescence Complementation. ACS Omega (2024)385. Targeting autophagy in HCC treatment: exploiting the CD147 internalization pathway. Cell Commun Signal (2024)386. Inhibition of XIST restrains paclitaxel resistance in breast cancer cells by targeting hsa-let-7d-5p/ATG16L1 through regulation of autophagy. Cell Signal (2024)387. Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration. Cancer Cell Int (2023)388. Helicobacter pylori promotes gastric cancer progression by activating the TGF-β/Smad2/EMT pathway through HKDC1. Cell Mol Life Sci (2024)389. Sustained Endocytosis Inhibition via Locally‐Injected Drug‐Eluting Hydrogel Improves ADCC‐Mediated Antibody Therapy in Colorectal Cancer. Adv Sci (Weinh) (2024)390. WNT7B promotes cancer progression via WNT/β-catenin signaling pathway and predicts a poor prognosis in oral squamous cell carcinoma. BMC Oral Health (2024)391. METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer. J Exp Clin Cancer Res (2024)392. Transcription factor TCF7L1 targeting HSPB6 is involved in EMT and PI3K/AKT/mTOR pathways in bladder cancer. J Biol Chem (2024)393. Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRASG12C inhibitor resistant tumors. Redox Biol (2024)394. Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics. Cell Death Dis (2024)395. The Activation of p300 Enhances the Sensitivity of Pituitary Adenomas to Dopamine Agonist Treatment by Regulating the Transcription of DRD2. International Journal of Molecular Sciences (2024)396. ΔNp63α promotes radioresistance in esophageal squamous cell carcinoma through the PLEC-KEAP1-NRF2 feedback loop. Cell Death Dis (2024)397. Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma. J Immunother Cancer (2024)398. PFKP silencing suppresses tumor growth via the AXL-MET axis. International Journal of Biological Sciences (2024)399. Olaparib Enhances the Efficacy of Third‐Generation Oncolytic Adenoviruses Against Glioblastoma by Modulating DNA Damage Response and p66shc‐Induced …. CNS Neurosci Ther (2024)400. The tumor suppressor SALL2 opposes chemotherapeutic resistance in breast cancer. Mol Cell Biochem (2024)401. Inhibition of NPC1 suppresses cell proliferation and β-catenin signaling activation of liver cancer. J Cancer Res Clin Oncol (2024)402. The KLF16/MYC feedback loop is a therapeutic target in bladder cancer. J Exp Clin Cancer Res (2024)403. Gallium-68 Labeled Positron Emission Computed Tomography Tracer Targeting Glypican-3 with High Contrast for Hepatocellular Carcinoma Imaging. ACS Pharmacology & Translational Science (2024)404. Raddeanin A Inhibits Colorectal Cancer Growth and Ameliorates Oxaliplatin Resistance Through the WNT/β-Catenin Signaling Pathway. Cancer Biother Radiopharm (2024)405. CEACAM6 facilitates gastric cancer progression through upregulating SLC27A2. Gene Therapy (2024)406. Preclinical evaluation of 89Zr/177Lu-labeled amatuximab for theranostic application in pancreatic ductal adenocarcinoma. Int J Pharm (2024)407. Disruption of Ferroptosis Inhibition and Immune Evasion with Tumor‐Activatable Prodrug for Boosted Photodynamic/Chemotherapy Eradication of Drug‐Resistant …. Adv Healthc Mater (2024)408. Preclinical characterization of XB002, an anti-tissue factor antibody-drug conjugate for the treatment of solid tumors. Mol Cancer Ther (2024)409. Targeting the SPC25/RIOK1/MYH9 Axis to Overcome Tumor Stemness and Platinum Resistance in Epithelial Ovarian Cancer. Adv Sci (Weinh) (2024)410. Targeting SPP1-orchestrated neutrophil extracellular traps-dominant pre-metastatic niche reduced HCC lung metastasis. Exp Hematol Oncol (2024)411. Targeting G-quadruplex by TMPyP4 for inhibition of colorectal cancer through cell cycle arrest and boosting anti-tumor immunity. Cell Death Dis (2024)412. Donor Substitution Engineering of Hemicyanine Nanoparticles to Reprogram the Tumor Microenvironment and Enhance Fn14‐Targeted BiTE for Glioblastoma …. Advanced Functional Materials (2024)413. Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4. Communications biology (2025)414. ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation. Nature chemical biology (2025)415. Salt‐inducible kinase 2 confers radioresistance in colorectal cancer by facilitating homologous recombination repair. MedComm (2025)416. Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance. Nature chemical biology (2025)417. The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis. Signal transduction and targeted therapy (2025)418. Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair. Cell death & disease (2025)419. Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway. Journal of advanced research (2025)420. Targeting aldehyde dehydrogenase ALDH3A1 increases ferroptosis vulnerability in squamous cancer. Oncogene (2025)421. High‐Valence Selenium Nanotherapeutics Downregulates MUC16 to Drive Precise Ovarian Cancer Therapy through Redox Perturbation. Advanced Functional Materials (2025)422. ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer. Scientific reports (2025)423. Improved Efficacy of Triple‐Negative Breast Cancer Immunotherapy via Hydrogel‐Based Co‐Delivery of CAR‐T Cells and Mitophagy Agonist. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)424. ADAR1 Promotes the Progression and Temozolomide Resistance of Glioma Through p62‐Mediated Selective Autophagy. CNS neuroscience & therapeutics (2025)425. ERK–USP9X-coupled regulation of thymidine kinase 1 promotes both its enzyme activity-dependent and its enzyme activity-independent functions for tumor growth. Nature structural & molecular biology (2025)426. MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway. Tissue & cell (2025)427. Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma. Cell death & disease (2025)428. PRMT6 promotes colorectal cancer progress via activating MYC signaling. Journal of translational medicine (2025)429. Exosomal miR-224-3p promotes lymphangiogenesis and lymph node metastasis by targeting GSK3B in gastric cancer. Oncology research (2025)430. Quercetin prevents the loss of chondrogenic capacity in expansion cultured human auricular chondrocytes by alleviating mitochondrial dysfunction. Regenerative therapy (2025)431. The Selective WEE1 Inhibitor Azenosertib Shows Synergistic Antitumor Activity with KRASG12C Inhibitors in Preclinical Models. Cancer research communications (2025)432. MTHFD2 Enhances cMYC O-GlcNAcylation to Promote Sunitinib Resistance in Renal Cell Carcinoma. Cancer research (2025)433. METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression. Cell death & disease (2025)434. Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)435. Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors. Med (New York, N.Y.) (2025)436. Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability. Theranostics (2025)437. Inhibition of METTL14 overcomes CDK4/6 inhibitor resistance driven by METTL14-m6A-E2F1-axis in ERα-positive breast cancer. Journal of nanobiotechnology (2025)438. Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation. Nature communications (2025)439. The hybrid lipoplex induces cytoskeletal rearrangement via autophagy/RhoA signaling pathway for enhanced anticancer gene therapy. Nature communications (2025)440. circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4. Molecular cancer (2025)441. Development of dual aptamers-functionalized c-MET PROTAC degraders for targeted therapy of osteosarcoma. Theranostics (2025)442. JARID1D-dependent androgen receptor and JunD signaling activation of osteoclast differentiation inhibits prostate cancer bone metastasis through demethylating H3K4. Theranostics (2025)443. VCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8+T cells function in the HCC microenvironment. Signal transduction and targeted therapy (2025)444. Preclinical evaluation of 68Ga‐labeled peptides for targeting CD44 imaging. (2025)445. Peptide-drug conjugates repolarize glioblastoma-associated macrophages to resensitize chemo-immunotherapy of glioblastoma. Science advances (2025)446. Dynamic Col-HZ Hydrogel with efficient delivery of bioactivator promotes ECM deposition and cartilage formation. Materials today. Bio (2025)447. RNF114 Interacts with EWSR1 to Regulate VEGFR2 in HER2-positive Breast Cancer. Journal of Cancer (2025)448. Efficacy and mechanism of the XPO1 inhibitor selinexor combined with decitabine in T-cell lymphoblastic lymphoma. Annals of hematology (2025)449. Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer. Molecular cancer (2025)450. Suppression of CYLD by HER3 confers ovarian cancer platinum resistance via inhibiting apoptosis and by inducing drug efflux. Experimental hematology & oncology (2025)451. MATN1-AS1 Promotes Tumour Metastasis and Sunitinib Resistance via E2F2 in Clear Cell Renal Cell Carcinoma. Journal of cellular and molecular medicine (2025)452. Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters. Cellular & molecular biology letters (2025)453. Thiostrepton suppresses intrahepatic cholangiocarcinoma progression via FOXM1-mediated tumor-associated macrophages reprogramming. Translational oncology (2025)454. KAT7-acetylated YBX1 promotes hepatocellular carcinoma proliferation by reprogramming nucleotide metabolism. BMC cancer (2025)455. Targeting capture and eradicate circulating tumor cells by activated platelet derived vehicle for inhibiting triple-negative breast cancer metastasis. Materials today. Bio (2025)456. AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple-Negative Breast Cancer. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)457. CRISPR-dCas9-Mediated PTEN Activation via Tumor Cell Membrane-Coated Nanoplatform Enhances Sensitivity to Tyrosine Kinase Inhibitors in Nonsmall Cell Lung Cancer. ACS applied materials & interfaces (2025)458. Neuropathiazol induces neuronal-like differentiation in neuroblastoma cells via upregulation of PEG5. Pediatric research (2025)459. Engineering IGF2 for Lysosome-targeting chimeras development to target drug-resistant membrane proteins in tumor therapy. Protein science : a publication of the Protein Society (2025)460. GABA regulates metabolic reprogramming to mediate the development of brain metastasis in non-small cell lung cancer. Journal of experimental & clinical cancer research : CR (2025)461. The splicing factor SRRM2 modulates two S6K kinases to promote colorectal cancer growth. Oncogene (2025)462. Imaging CDK4/6 Broaden Options of Breast Cancer Diagnostics with Positron Emission Tomography. Journal of medicinal chemistry (2025)463. ZCCHC4 regulates esophageal cancer progression and cisplatin resistance through ROS/c-myc axis. Scientific reports (2025)464. The FBXW7-RPAP2 Axis Controls the Growth of Hepatocellular Carcinoma Cells and Determines the Fate of Liver Cell Differentiation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)465. Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)466. Nanovesicles for Lipid Metabolism Reprogram-Enhanced Ferroptosis and Magnetotherapy of Refractory Tumors and Inhibiting Metastasis with Activated Innate Immunity. ACS nano (2025)467. Multi-omics analyses reveal biological and clinical insights in recurrent stage I non-small cell lung cancer. Nature communications (2025)468. The E3 ubiquitin ligase MAEA promotes macrophage phagocytosis and inhibits gastrointestinal cancer progression by mediating PARP1 ubiquitination and degradation. International journal of biological sciences (2025)469. Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer. Cell death discovery (2025)470. CircSATB1 Promotes Colorectal Cancer Liver Metastasis through Facilitating FKBP8 Degradation via RNF25-Mediated Ubiquitination. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)471. Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC. Cell death & disease (2025)472. Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway. International journal of nanomedicine (2025)473. Targeting the splicing factor SNRPB inhibits endometrial cancer progression by retaining the POLD1 intron. Experimental & molecular medicine (2025)474. Targeting FDFT1 Reduces Cholesterol and Bile Acid Production and Delays Hepatocellular Carcinoma Progression Through the HNF4A/ALDOB/AKT1 Axis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)475. Stimulus-activated ribonuclease targeting chimeras for tumor microenvironment activated cancer therapy. Nature communications (2025)476. NIR-II Fluorescent Thermophoretic Nanomotors for Superficial Tumor Photothermal Therapy. Advanced materials (Deerfield Beach, Fla.) (2025)477. FBXW7/GSK3β-mediated proline-rich 11 degradation promotes oxidative DNA damage and inhibits tumor progression in renal cell carcinoma. Theranostics (2025)478. STX17-DT facilitates axitinib resistance in renal cell carcinoma by inhibiting mitochondrial ROS accumulation and ferroptosis. Cell death & disease (2025)479. Targeting USP1 Potentiates Radiation-Induced Type I IFN-Dependent Antitumor Immunity by Enhancing Oligo-Ubiquitinated SAR1A-Mediated STING Trafficking and Activation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)480. Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation. Theranostics (2025)481. Hepatic factor MANF drives hepatocytes reprogramming by detaining cytosolic CK19 in intrahepatic cholangiocarcinoma. Cell death and differentiation (2025)482. Enzymatically responsive nanocarriers targeting PD-1 and TGF-β pathways reverse immunotherapeutic resistance and elicit robust therapeutic efficacy. Journal of nanobiotechnology (2025)
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