- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions. - Animal Models
KO/cKO Mouse
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Strain NO.T037004Gene Humanized
BALB/c-hPD1/hPDL1/hTIGIT
Featured
FeaturedStatus
Strain NO.
T037004
Strain Name
BALB/c-hPD1/hPDL1/hTIGIT
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GenePDCD1
- Gene Full NameCD274 antigen,CD274 molecule,T cell immunoreceptor with Ig and ITIM domains,programmed cell d
- Gene AliasB7h1,Pdl1,Pdcd1l1,Pdcd1lg1,A530045L16Rik,B7-H,B7H1,PDL1,PD-L1,hPD-L1,PDCD1L1
- NCBI
- Research FieldHumanized model, Gene humanization model, Humanization of tumor targets
- Domain Description1. Screening and efficacy evaluation of TIGIT inhibitors and PD1 inhibitors，such as screening of oncology therapeutics or neutralizing antibodies 2. Immune tolerance inhibitor screening 3. Preclinical toxicity evaluation 4. Development of combinations of TIGIT-targeted drugs and PD1/PDL1 inhibitors 5. Immune system related studies.
Product Details
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