- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions. - Animal Models
KO/cKO Mouse
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Strain NO.T006929Gene Humanized
B6-hPD1/hSIRPα
Featured
FeaturedStatus
Strain NO.
T006929
Strain Name
B6-hPD1/hSIRPα
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GenePDCD1
- Gene Full Namesignal-regulatory protein alpha,signal regulatory protein alpha,rogrammed cell death 1,prog
- Gene AliasAI835480,Bit,CD172a,P84,Ptpns1,SHP-1,SHPS-1,SIRP,BIT,CD172A,MFR,MYD
- NCBI
- MGI
- Research FieldHumanized model, Gene humanization model, Humanization of tumor targets
- Domain Description1. Screening of hSIRPαor hPD1 inhibitors 2.Efficacy and safety evalation of the combination of hSIRPα and hPD1 inhibitors 3.Immune system related studies.
Product Details
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