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Strain NO.T006213Gene Humanized

B6-hPD1/hCSF1R
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Status
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Strain NO.
T006213
Strain Name
B6-hPD1/hCSF1R
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    PDCD1
  • Gene Full Name
    programmed cell death 1,colony stimulating factor 1 receptor
  • Gene Alias
    PD-1,Pdc1,Ly101,PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,Fms,Fim2,CD115,C
  • NCBI
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Screening and efficacy evaluation of CSF1R inhibitor or PD1 inhibitor, such as anti-tumor drugs or neutralizing antibody screening 2. Screening of immune tolerance inhibitors 3. Preclinical toxicity evaluation 4. Development of the combiantion of CSF1R-targeted drugs and PD1 inhibitors 5. immune system related studies.
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