- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions. - Animal Models
KO/cKO Mouse
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Strain NO.T004993Disease Models
FVB-MMTV-PyMT
Featured
FeaturedStatus
13Strain NO.
T004993
Strain Name
FVB-MMTV-PyMT
Background
FVB/NJGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of Gene/
- Gene Full Namefamily with sequence similarity 89, member B
- Gene Alias1110021A21Rik,MMTV,Mtvr2
- NCBI
- MGI
- Research FieldTumor model, Disease Models, Spontaneous tumor
- Domain Description1. Oncology research (breast cancer) 2. Screening of small molecule drugs for breast cancer.
Product Details
150%
1/0
Published Literature- 2022Brown-fat-mediated tumour suppression by cold-altered global metabolismNature
- 2023Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII(hi) neutrophilsSignal Transduct Target Ther
- 2025A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapyNature nanotechnology
- 2023A circular RNA activated by TGFbeta promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stabilityNat Commun
- 2025Therapeutic Black Phosphorus Nanosheets Elicit Neutrophil Response for Enhanced Tumor SuppressionAdvanced science (Weinheim, Baden-Wurttemberg, Germany)
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