BALB/c-hPD1/hTIGIT

General Information

Official Name Of Gene
PDCD1
Gene Full Name
programmed cell death 1,T cell immunoreceptor with Ig and ITIM domains
Gene Alias
PD-1,Pdc1,Ly101,PD1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,Vstm3,VSIG9,VSTM3,WUCAM
NCBI
5133 201633 18566 100043314
Research Field
Humanized model, Gene humanization model, Humanization of tumor targets
Domain Description
1. Screening and efficacy evaluation of TIGIT inhibitors or PD1 inhibitors, such as anti-tumor drugs or neutralizing antibody screening 2. Immune tolerance inhibitors screening 3. Preclinical toxicity evaluation 4. Development of the combination of TIGIT-targeted drugs and PD1 inhibitors 5. Immune system related research.