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Strain NO.T036669Immunodeficient

NCG-M
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Status
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Strain NO.
T036669
Strain Name
NCG-M
Background
NOD/ShiLtJGpt
Microbial Grade
Specific pathogen free (SPF)
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model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    CSF2
  • Gene Full Name
    colony stimulating factor 2,interleukin 3,KIT ligand
  • Gene Alias
    CSF,GMCSF,IL-3,MCGF,MULTI-CSF,SF,MGF,SCF,SLF,DCUA,FPH2,FPHH,KL-1,Kitl,S
  • NCBI
    1437 3562 4254 14910
  • Chromosome
    6
  • Research Field
    Humanized model, Immunodeficiency, Humanization of the immune system
  • Domain Description
    1. Supporting the reconstitution of multispectral human-derived immune cells in mice after CD34+ hematopoietic stem cell transplantation, including myeloid cells and regulatory T cell populations 2. For the establishment of acute myeloid leukemia (AML) PDX mouse models 3. Inoculation of human-derived tumors for drug screening 4. Cytokine storm and immunotoxicity response studies.
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