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Strain NO.T001475Immunodeficient

NCG
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Status
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Strain NO.
T001475
Strain Name
NCG
Background
NOD/ShiLtJGpt
Microbial Grade
Specific pathogen free (SPF)
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model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    Prkdc
  • Gene Full Name
    protein kinase, DNA activated, catalytic polypeptide,interleukin 2 receptor, gamma chain
  • Gene Alias
    DNA-PKcs,DNAPDcs,DNAPK,DNPK1,DOXNPH,HYRC1,XRCC7,dxnph,p460,scid,slip,CD132,[g]c,gamma(c),gc,p64
  • NCBI
    19090 16186
  • MGI
    10477996551
  • Chromosome
    16X
  • Research Field
    Humanized model, Immunodeficiency, Humanization of the immune system
  • Domain Description
    1. Immune reconstituted mouse models, such as BLT humanized mice, PBMC humanized mice and CD34+ humanized mice 2. Human-derived tumor cells and xenograft transplantation (CDX, PDX) 3. Drug efficacy evaluation (small molecule drugs, macromolecular drugs and combination drug therapy) 4. Human cancer models 5. Stem cell research.
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