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Strain NO.T055631Gene Humanized

B6-hDLL4
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Status
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Strain NO.
T055631
Strain Name
B6-hDLL4
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    DLL4
  • Gene Full Name
    delta like canonical Notch ligand 4,delta like canonical Notch ligand 4
  • Gene Alias
    AOS6,delta4,hdelta2,Delta4
  • NCBI
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Evaluation of the efficacy of human DLL4 inhibitors, e.g. screening for human DLL4 neutralizing antibodies or small molecule drugs that inhibit human DLL4 activity 2. Safety evaluation of anti-human DLL4 antibodies 3. Immunotherapy studies
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