- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions.
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Strain NO.T052929Gene Humanized
B6-hPDL1/hB7H3
Featured
FeaturedStatus
Strain NO.
T052929
Strain Name
B6-hPDL1/hB7H3
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GeneCD274
- Gene Full NameCD274 antigen,CD276 antigen
- Gene AliasA530045L16Rik,B7h1,Pdcd1l1,Pdcd1lg1,Pdl1,6030411F23Rik,AU016588,B7RP-2,B7h3
- NCBI
- MGI
- Chromosome9
- Research FieldHumanized model, Gene humanization model, Humanization of tumor targets
- Domain Description1. Screening and efficacy evaluation of PDL1/B7H3 inhibitors and antibodies，such as screening of oncology therapeutics or neutralizing antibodies 2. Development of Hcombinations of PDL-targeted drugs and B inhibitors.PDL1靶向药物与B7H3靶向药物联合用药的筛选开发3.immune system related studies.
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