In Vivo Drug Efficacy Evaluation

List of Mouse Models for Neurological Diseases

Neurological Disease		Model Name	Model Number	Model Type
Alzheimer's Disease(AD) Models		FAD^2T(APP/PS1)	T005625	Transgenic
		FAD^{3T(APP/PS1/Tau)}	T049751	Transgenic
		FAD^4T	T053302	Transgenic
Humanized Alzheimer's Disease (AD) Models		FAD^4T-hTREM2	T058996	Transgenic
		FAD^4T-hAPOE3	T065022	Transgenic
		FAD^4T-hAPOE4	T064971	Transgenic
Parkinson's Disease (PD) Models		hSNCA A53T	T054329	Transgenic
		hSNCA E46KA53T	T054322	Transgenic
		B6-Tfam-flox/Slc6a3-Cre	T053276	Transgenic
		6-OHDA-induced PD model	/	Induced
Huntington's Disease (HD) Models		hHTT CAG130-N	T054804	Transgenic
Amyotrophic Lateral Sclerosis (ALS) Models		hSOD1G93A	T055223	Transgenic
Amyotrophic Lateral Sclerosis (ALS) Models		hTDP43wtxA315T	T054620	Transgenic
Transthyretin Amyloidosis (ATTR) Models		hTTR KI	T055186	Knock in
		hTTR V30M Tg	T059897	Transgenic
		hTTR V30M Tg:ttr KO	T059956	Transgenic
Duchenne Muscular Dystrophy (DMD) Models		B10-Dmd-KO	T003035	Knock out
		Dmd C3197T	T014593	Point Mutation
		B6-Dmd Del45	T056002	Knock out
		B6-Dmd Del50	T056003	Knock out
		B6-Dmd Del51	T056004	Knock out
		B6-Dmd Del52	T049591	Knock out
Delivering Therapeutics Across the Blood-Brain Barrier (BBB) --Transferrin receptor		B6-hTFRC	T067796	Knock in
		FAD^4T-h/m TFRC	T065962	Transgenic
		FAD^3T-h/m TFRC	T065963	Transgenic
Pain Mouse Models	Inflammatory Pain	Formalin-induced Acute Inflammatory Pain	/	Induced
	Inflammatory Pain	Complete Freund's Adjuvant(CFA)-induced Mechanical Allodynia	/	Induced
	Neuropathic pain	Sciatic nerve crush	/	Induced
	Chemotherapy-induced Peripheral Neuropathy	Vincristine-Induced Peripheral Neuropathy	/	Induced
		Oxaliplatin-Induced Peripheral Neuropathy	/	Induced
		Paclitaxel-Induced Peripheral Neuropathy	/	Induced
	Diabetic Peripheral Neuropathy	MLDS-induced Diabetic Peripheral Neuropathy	/	Induced
	Migraine	Nitroglycerin-induced Migraine-like Pain	/	Induced

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