head-icon1.svgMeet us at an upcoming event
head-icon2.svgIn Stock. Ready to Ship
languageEN
languageEN
icon-arrow-g
counsellingContact Us
languageEN
languageEN
icon-arrow-g
header-bg-mouse-01b.jpg

Germ-Free Mice

Browse Modelsarrow-right-warrow-right-g
Why Usarrow-right-warrow-right-g
Explore

Featured Germ-Free Mouse Models

Explore germ-free mouse models for microbiome, host-microbe interaction, disease mechanism, and preclinical research.

Show more icon-arrow-g
Models

All Germ-Free Mouse Models

Product Models
Content filteringarrow
res?.all_product?.table_th_info
  • 1
FAQ

Frequently Asked Questions About Germ-Free Mice

What are germ-free (GF) mice?

Germ-free (GF) mice are laboratory animals with no detectable living microorganisms or parasites, internally or externally, based on currently available detection methods. Maintaining GF mice requires rigorous microbial control, specialized environments, and dedicated equipment.

What are the characteristic differences between germ-free (GF) and specific pathogen-free (SPF) mice?

In comparison to conventional SPF mice, GF mice exhibit notable physiological and morphological changes, such as an enlarged cecum, thinned intestinal musculature, reduced liver and heart size, weakened innate immune response, and high susceptibility to microbial infections.

Why use germ-free (GF) mice in scientific research?

Germ-free mice help researchers investigate causal relationships between the microbiome and disease and study how microorganisms influence host physiology. Because these mice lack detectable microorganisms, researchers can use them as a controlled baseline or introduce specific microbial communities to test targeted hypotheses.

Explore

Recommended for You

Discover more models, courses, and resources to accelerate your research

Model
Genetically Engineered Models
arrow-right-garrow-right-w
Model
Core Research Strains
arrow-right-garrow-right-w
On This Page
  • Featured Germ-Free Mouse Models
  • Models
  • FAQ
  • Recommended for You

background-image

Find Models

Contact Our Teamarrow-right-garrow-right-w
Recommended Content
close

Submit Inquiry

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

State/Province*

City

Area of interest*

Select Area of Interest

Research Focus

Additional Info

Submitarrowarrow

Contact Us

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

State/Province*

City

Area of interest*

Select Area of Interest

Research Focus

How did you hear about us*

Select a source

Leave us a message*

Submitarrowarrow

Schedule a Meeting

Let us know which event you're attending and we'd be happy to connect with you.

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

State/Province*

City

Area of interest*

Select Area of Interest

Research Focus

How did you hear about us*

Select a source

Leave us a message

Submitarrowarrow

Download

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

State/Province*

City

Research Focus

Submitarrowarrow

Download

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

State/Province*

City

Research Focus

Submitarrowarrow

Watch On-Demand Webinar

First Name*

Last Name*

Organization*

Email*

Country/Region

Select Country/Region

State/Province*

City

Research Focus

Submitarrowarrow

Newsletter Signup

First Name*

Last Name*

Organization*

Email*

Country/Region*

Select Country/Region

Area of interest*

Select Area of Interest

Research Focus

Submitarrowarrow