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Strain NO.T055501Gene Humanized

BALB/c-hPD1/hPDL1/hLAG3/hTIGIT
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Status
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Strain NO.
T055501
Strain Name
BALB/c-hPD1/hPDL1/hLAG3/hTIGIT
Background
BALB/cJGpt
Microbial Grade
Specific pathogen free (SPF)
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model-detail-box2-icon1.svgGeneral Information
  • Official Name Of Gene
    PDCD1
  • Gene Full Name
    programmed cell death 1,lymphocyte-activation gene 3,T cell immunoreceptor with Ig and ITIM domains
  • Gene Alias
    Ly101,PD-1,Pdc1,CD223,LAG-3,Ly66,Vstm3
  • NCBI
    5133 29126 3902 201633 18566 60533 16768 100043314
  • MGI
    1048791065883642260
  • Research Field
    Humanized model, Gene humanization model, Humanization of tumor targets
  • Domain Description
    1. Screening and efficacy evaluation of hPD1, hPDL1, hLAG3 or hTIGIT inhibitors 2. Development of hLAG3- and TIGIT-targeted drugs in combination with PD1/PDL1 drugs 3. Anti-tumor efficacy evaluation of targeted drugs and combination drugs 4. Autoimmune disease research.
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