BALB/c-hPD1/hPDL1/hTIGIT/hCTLA4

General Information

Official Name Of Gene
PDCD1
Gene Full Name
programmed cell death 1,CD274 molecule,T cell immunoreceptor with Ig and ITIM domains,cytotoxic T-lymphocyte associated protein 4
Gene Alias
PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,B7-H,B7H1,PDL1,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,VSIG9,VSTM3,WUCAM,CD,GSE,GRD4,ALPS5,CD152,CTLA-4,IDDM12,CELIAC3
NCBI
5133 29126 201633 1493 18566 60533 100043314 12477
Research Field
Humanized model, Gene humanization model, Humanization of tumor targets
Domain Description
1. Efficacy evaluation of hPD1, hPDL1, hTIGIT and hCTLA4 inhibitors as well as their combination 2. Safety evaluation of anti-hPD1, anti-hPDL1, anti-TIGIT and anti-hCTLA4 antibodies 3.Immune system related studies 4. Anti-tumor research 5. Autoimmune disease research.