- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions.
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Strain NO.T015188KOAP Mice
Slc7a11-flox
Featured
FeaturedStatus
4Strain NO.
T015188
Strain Name
Slc7a11-flox
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GeneSlc7a11
- Gene Full Namesolute carrier family 7 (cationic amino acid transporter, y+ system), member 11
- Gene Alias9930009M05Rik,AI451155,sut,xCT
- NCBI
- MGI
- Chromosome3
- Research FieldMetabolic research, Developmental Biology, immune system, integument, Tumor research, nervous system, Signal Transduction, vision/eye, Cell Proliferation, Cell death, Cytoskeleton, Physiological system, homeostasis/metabolism, Cell biology, Molecular biology, cellular, hematopoietic system, pigmentation, Cell localization, endoplasmic reticulum, Organelles membrane, transporter
Product Details
150%
1/0
Published Literature- 2026SLC7A11 deficiency exacerbates systemic lupus erythematosus by inducing instability and ferroptosis in regulatory T cellsCommunications biology
- 2024The Intestinal Transporter SLC30A1 Plays a Critical Role in Regulating Systemic Zinc HomeostasisAdv Sci (Weinh)
- 2024Essentiality of SLC7A11-mediated nonessential amino acids in MASLDScience Bulletin
- 2023Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytesRedox Rep
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