- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions.
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Strain NO.T006873Gene Humanized
B6-hPD1/hPDL1/hTIGIT
Featured
FeaturedStatus
Strain NO.
T006873
Strain Name
B6-hPD1/hPDL1/hTIGIT
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GenePDCD1
- Gene Full NameCD274 antigen,CD274 molecule,T cell immunoreceptor with Ig and ITIM domains,programmed cell d
- Gene AliasB7h1,Pdl1,Pdcd1l1,Pdcd1lg1,A530045L16Rik,B7-H,B7H1,PDL1,PD-L1,hPD-L1,PDCD1L1
- NCBI
- MGI
- Research FieldHumanized model, Gene humanization model, Humanization of tumor targets
- Domain Description1. Screening and efficacy evaluation of TIGIT inhibitors or PD1 inhibitors, such as anti-tumor drugs or neutralizing antibody screening 2. Preclinical toxicity evaluation 3. Development of the combination of TIGIT-targeted drugs and PD1/PDL1 inhibitors 4. Screening of immune tolerence inhibitors 5. Immune system related research.
Product Details
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