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Oncology

Development and Application of the NCG-hIL2 Mouse Model: A Humanized Platform for Enhanced NK Cell Evaluation in ADCC Efficacy Testing

2024-04-10

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The NCG-hIL2 mouse model, engineered to express human Interleukin-2 (IL2), facilitates the reconstitution of human NK cells, aiding in the assessment of therapeutic antibodies' efficacy, notably in ADCC. This model enhances our understanding of NK cell development and serves as a valuable tool for studying immunotherapies, particularly in cancer treatment.


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