- By Indication
Inflammatory and Autoimmune DiseasesRespiratory DiseasesInfectious DiseasesRare DiseaseGut Microbiota Research ServiceBy Modality
Preclinical Model Strategies for T-Cell Engagers: From Oncology to Autoimmune Disease
2026-10-27
11:00 AM ET
Dr. Wanjun Yuan & Dr. Haiqiao SunOne TCE Modality. Two Disease Contexts. Different Preclinical Questions.
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Strain NO.T012747KOAP Mice
Sting1-KO
Featured
FeaturedStatus
23Strain NO.
T012747
Strain Name
Sting1-KO
Background
C57BL/6JGpt
Microbial Grade
Specific pathogen free (SPF)
General Information- Official Name Of GeneSting1
- Gene Full Namestimulator of interferon response cGAMP interactor 1
- Gene Alias2610307O08Rik,ERIS,MPYS,Mita,STING,STING-beta,Tmem173
- NCBI
- MGI
- Chromosome18
- Research FieldMetabolic research, Developmental Biology, immune system, integument, respiratory system, DNA transcription, digestive/alimentary system, Mitochondrial research, Physiological system, homeostasis/metabolism, Cell biology, Molecular biology, cellular, hematopoietic system, mortality/aging, Cytoplasmic vesicle, endoplasmic reticulum, endosome, Golgi apparatus, cell nucleus, cytomembrane, Organelles membrane
- Domain Description1. Research related to deficiency of STING protein. 2. Study of human diseases associated with STING.
Product Details
150%
1/0
Published Literature- 2026Interferon-λ drives renal fibrosis by coordinating epithelial-fibroblast crosstalkJ Exp Med
- 2026African swine fever virus B66L drives extracellular mitochondrial release to promote systemic inflammation in miceNature communications
- 2025Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapyNature communications
- 2026Contribution of the STING in macrophages to the pulmonary inflammation and fibrosisInternational immunopharmacology
- 2025Herpes simplex virus type 1 disseminates from the cornea to the CNS in mice by thwarting type III interferon immune defensesCell reports
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