B6-Mdr1a/Mdr1b KO

General Information

Official Name Of Gene
Abcb1a
Gene Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 1A,ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Gene Alias
Abcb4, Evi32, Mdr1a, Mdr3, P-gp, Pgp, Pgy-3, Pgy3, mdr-3,Abcb1, Mdr1, Mdr1b, Pgy-1, Pgy1, mdr
NCBI
18671 18669
Research Field
Neurodegenerative diseases, Disease Models
Domain Description
1. Investigate central neurotoxicity of compounds. 2. Study the pharmacological activity associated with the use of Pglycoprotein inhibitors in drug therapies. 3. Study on multidrug resistance of Mdr1a/b (P-glycoprotein) to cancer cells.