BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Pcxem1Cflox/Gpt |
| Strain Number: | T008093 |
| Official Symbol: | Pcx |
| Strain Strategy: | T008093.Pcx Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | pyruvate carboxylase |
| Also Known As: | Pc,Pcb |
| NCBI Number: | 18563 |
| MGI Number: | 97520 |
| Chromosome: | 19 |
| Distance Between Two Loxps: | 6055bp |
| Research Areas: | Metabolic research,Lipid Metabolism,Developmental Biology,mortality/aging,nervous system,behavior/neurological,Physiological system,hematopoietic system,Cell biology,Mitochondrial research,cytomembrane,Molecular biology,ligase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008093.Pcx Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway. Adv Sci (Weinh) (2025) |
| Gene Family: | MicroRNA protein coding host genes |