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B6/JGpt-Apoeem1Cd82/Gpt
Apoe-KO|Strain
NO.T001458
Knockout (KO)
- 性别： --
- 周龄： --
- 基因型： --
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B6/JGpt-Apoeem1Cd82/Gpt
Apoe-KO|Strain
NO.T001458
Knockout (KO)
性 别
周 龄
基因型
*以发货时库存基因型为准
小鼠分类
- 选择数量：
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- 基本信息
- 销售状态：IF(正常销售)
- 保存方式： 活体,冷冻
- 品系背景：[N000013] C57BL/6JGpt
- 微生物等级： SPF级
- 品系策略： 登录后查看品系策略，点我登录
- 品系策略： T001458.Apoe-KO 品系资料.pdf T001458.Apoe-KO strain Info.pdf
- 研究领域：代谢研究,脂肪组织,蛋白质代谢,内稳态/代谢,脂代谢,发育生物学,细胞分化,增长/尺寸/体型,死亡/衰老,免疫系统,神经系统,视力/眼睛,听力/耳,味觉和嗅觉,行为/神经,神经突出,生理系统,皮肤,心血管系统,骨骼系统,肌肉,呼吸系统,消化系统,肝脏/胆道系统,肾和泌尿系统,内/外分泌腺,造血系统,细胞生物学,细胞增殖,细胞死亡,细胞骨架,细胞组成,细胞定位,细胞质囊泡,内质网,核内体,高尔基体,细胞核,细胞膜,细胞器膜,分子生物学,信号转导,DNA转录,酶活性调节,脂质结合蛋白,转运蛋白
- 领域描述：1.心血管疾病研究：动脉粥样硬化.高胆固醇血症.高血脂症2.脂代谢研究3.神经生物学研究：阿尔兹海默症.行为及学习障碍.神经退行性疾病。
- 发表文献：
Nicotine modulates CTSS (cathepsin S) synthesis and secretion through regulating the autophagy-lysosomal machinery in atherosclerosis https://doi.org/10.1161/ATVBAHA.120.314053 LncRNA NORAD promotes vascular endothelial cell injury and atherosclerosis through suppressing VEGF gene transcription via enhancing H3K9 deacetylation by recruiting HDAC6 https://doi.org/10.3389/fcell.2021.701628 Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway https://doi.org/10.3390/antiox10060916 Targeting macrophage liver X receptors by hydrogel‐encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis https://doi.org/10.1111/bph.15387 BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis https://doi.org/10.1016/j.redox.2021.101979 BTK Promotes Atherosclerosis by Regulating Oxidative Stress, Mitochondrial Injury, and ER Stress of Macrophages https://doi.org/10.1155/2021/9972413 ZBTB20 Positively Regulates Oxidative Stress, Mitochondrial Fission, and Inflammatory Responses of ox-LDL-Induced Macrophages in Atherosclerosis https://doi.org/10.1155/2021/5590855 circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis https://doi.org/10.3389/fcell.2021.652032 ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway https://www.thno.org/v11p1129.htm Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology https://doi.org/10.1111/imm.13401 Ablation of Plasma Prekallikrein Decreases LDL Cholesterol by Stabilizing LDL Receptor and Protects against Atherosclerosis https://doi.org/10.1161/CIRCULATIONAHA.121.056491 Qing-Xin-Jie-Yu Granule alleviates atherosclerosis by reshaping gut microbiota and metabolic homeostasis of ApoE-/- mice https://doi.org/10.1016/j.phymed.2022.154220 Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production https://doi.org/10.1016/j.cellsig.2022.110419 Dual-responsive targeted atherosclerosis therapy through a multi-effective nanoplatform with anti-inflammatory, lipid-regulating and autophagy https://doi.org/10.1016/j.cej.2022.140067 JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis https://doi.org/10.1186/s13045-022-01381-6 Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect https://doi.org/10.1186/s12951-022-01720-2 Natural Cell Patches: Melanin Nanoparticles for MR Imaging‐Guided Antiatherosclerosis Therapy via Attenuating Macrophage Pyroptosis https://doi.org/10.1002/adfm.202212748
*使用本品系发表的文献需注明：Apoe-KO mice（Strain NO.T001458）were purchased from GemPharmatech (Nanjing, China).
