Thrombosis Models
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Thrombosis refers to the formation of a blood clot, known as a thrombus, within a blood vessel. This clotting process can occur in both arteries and veins and has significant impacts on human health. Thrombosis mouse models are essential tools in biomedical research for studying the mechanisms of blood clot formation and evaluating potential anti-thrombotic therapies. GemPharmatech has successfully established an FeCl3-induced carotid thrombosis mouse model and a series of genetically-humanized mouse models that are engineered to express pivotal human coagulation factors, including Factor XI and Factor XII, which can be used in proof-of-concept studies.