Customized Germ-free Services

Custom Model Generation Services
Preclinical Testing Services
Anti-Tumor Drug Efficacy EvaluationAutoimmune Disease Efficacy EvaluationMetabolic Disease Efficacy EvaluationNeurological Disease Efficacy EvaluationCardiovascular Diseases Efficacy EvaluationBioanalytical ServicesPhenotyping ServicesNon-GLP Toxicity Assessment ServicesCell Therapy & Gene Therapy Efficacy EvaluationDisease Rat Models Infectious Disease Efficacy Evaluation
Germ-Free and Microbiome Services
Mouse-Derived Gut Microbiota LibraryCustomized Germ-free ServicesEvaluation of Anti-tumor Effect of Gut MicrobiotaMicrobiota Extraction and TransplantationGerm-free Rederivation and BreedingMicrobial Strain Culture and Colonization
Cell Lines and Customization Services
Cell Line Customization ServicesSyngeneic Cell LinesReporter Cell LinesCDX Cell Lines
Patient Derived Xenograft (PDX) Mouse Models and Efficacy Services
Custom Breeding Services
Customized Mice Breeding ServicesCryopreservation and ResuscitationAssisted ReproductionMouse Rederivation Service
Animal Quality Testing Services
SNP Testing ServicesMicrobiology Testing ServicesGenetic IntegrityAnimal HealthAnimal Welfare
NeoMab Fully-Human Antibody Discovery Service
Assay Capabilities
Molecular PlatformPK/PD PlatformPathological Diagnosis PlatformCell-based Service PlatformFlow Cytometry PlatformImaging and Analysis PlatformBehavioral Analysis Platform
Other Services
Animal Facility and HusbandryReproductive and Embryology Services Isolation of Embryonic Fibroblasts

GemPharmatech can supply a full set of proprietary germ-free housing apparatus and provide complete technical training to clients who are interested in establishing germ-free experimental platforms. We also provide services including customized sterility testing, aseptic instruments and mice feed. 

Microbiota studies are important in a number of research fields, and gut microbiota plays a key role in the onset, progression, and treatment of metabolic diseases, inflammatory bowel disease, tumor immunotherapy, and neurological disorders. Our germ-free mice and gut microbiome service platform can be used to explore the gut microbiome according to the client demands.


Microbiology ServicesIn Vivo ServicesIn vitro AnalysisBioinformatics

·Microbial Culture


·Fecal Microbiota extraction


·Single Strain/Flora Transplantation


·Bacterial Identification:

 Qualitative testing

 Quantitative testing

·Drug Delivery:

 Intraperitoneal, subcutaneous, oral gavage, intravenous.


·Blood Collection:

 Submandibular plexus, tail vein, retro-orbital.


·Observation:

 Body weight, blood glucose, food intake.


·Sample Collection:

 Blood, feces, urine.

·Cell Experiments:

 Cell isolation and culture

 Tumor cell line inoculation


·Flow Cytometry:

 Cell analysis

 Antibody binding assay


·Pathology Experiments:

 Staining and sectioning

 Immunohistochemistry


·Molecular Assays:

 ELISA/WB

 Blood Biochemistry

 CBC

·16s rRNA Amplicon Sequencing:

 OTU/ASV taxonomic analysis

 Community composition analysis

 Alpha diversity analysis

 Beta diversity analysis


·Metagenomic Sequencing:

 Species annotation and compositional profiling

 Gene prediction and functional annotation

 Alpha and Beta diversity analysis

 Key biomarker screening


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