Germ-free Rederivation and Breeding

Custom Model Generation Services
Preclinical Testing Services
Anti-Tumor Drug Efficacy EvaluationAutoimmune Disease Efficacy EvaluationMetabolic Disease Efficacy EvaluationNeurological Disease Efficacy EvaluationCardiovascular Diseases Efficacy EvaluationBioanalytical ServicesPhenotyping ServicesNon-GLP Toxicity Assessment ServicesCell Therapy & Gene Therapy Efficacy EvaluationDisease Rat Models Infectious Disease Efficacy Evaluation
Germ-Free and Microbiome Services
Mouse-Derived Gut Microbiota LibraryCustomized Germ-free ServicesEvaluation of Anti-tumor Effect of Gut MicrobiotaMicrobiota Extraction and TransplantationGerm-free Rederivation and BreedingMicrobial Strain Culture and Colonization
Cell Lines and Customization Services
Cell Line Customization ServicesSyngeneic Cell LinesReporter Cell LinesCDX Cell Lines
Patient Derived Xenograft (PDX) Mouse Models and Efficacy Services
Custom Breeding Services
Customized Mice Breeding ServicesCryopreservation and ResuscitationAssisted ReproductionMouse Rederivation Service
Animal Quality Testing Services
SNP Testing ServicesMicrobiology Testing ServicesGenetic IntegrityAnimal HealthAnimal Welfare
NeoMab Fully-Human Antibody Discovery Service
Assay Capabilities
Molecular PlatformPK/PD PlatformPathological Diagnosis PlatformCell-based Service PlatformFlow Cytometry PlatformImaging and Analysis PlatformBehavioral Analysis Platform
Other Services
Animal Facility and HusbandryReproductive and Embryology Services Isolation of Embryonic Fibroblasts

Given the presence of microbiota in SPF mice, it is hard to study the microbe-host interaction. To overcome this challenge, GemPharmatech has become the first to establish the germ-free embryo transfer technique in China. Nearly 20,000 germ-free strains can be obtained by sourcing KO or CKO strains from the GemPharmatech Knock Out All Project mouse strain library through our germ-free rederivation and breeding services.


Benefits：

  • Advanced purification technique: Our germ-free embryo transfer technique can eliminate microbial contamination and enhance purification.

  • Experienced technical team: Our yearly capacity is nearly 100 germ-free strains; a single batch of germ-free rederived progeny can meet the needs of multiple research projects.

  • Strict sterile environment: We have first-class sterile breeding facilities and strain management practices.

  • High success rate: Up to date, we have a 100% success rate in germ-free rederivation.

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