Autoimmune dermatoses are skin disorders where the immune system mistakenly attacks healthy skin cells, leading to inflammation and tissue damage. Common examples include psoriasis, atopic dermatitis and vitiligo. These conditions often involve cytokines, autoantibodies, and immune cell infiltration. Diagnosis relies on clinical examination, histopathology, and serological tests, while treatment strategy is aimed at suppressing abnormal immune responses with topical or systemic immunosuppressants, phototherapy, or biologics, targeting pathways like TNF-α, IL-17 or Th2 cytokines to alleviate symptoms and improve quality of life.
