Cell Cycle Experiments

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Case: In vitro pharmacological efficacy evaluation of ADC drug DS-8201a targeting HER2.

 

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Fig. The effects of different concentrations of DS-8201a on the cell cycle of the target cell SK-BR-3.

GPT Advantages


  • Extensive library of target cells (300+ cancer cell lines and humanized cell lines) and certified BSL-2 level laboratories.

  • Free provision of comparator antibody therapy for common viral infections.

  • Proficiency in Flow Cytometry and molecular analysis platforms.

  • Availability of immune system humanized mice for verifying the Fc effect (ADCC, ADCP, etc.) on ADC drug antibodies, including models like NCG-IL15, NCG-IL2, and NCG-SGM3.

  • Vast project experience.

  • Compliance with regulatory requirements for new drug application submissions.

  • Strict laboratory data storage standards to ensure experiment traceability.