BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Gpbar1em2Cd6318/Gpt |
| Strain Number: | T012754 |
| Official Symbol: | Gpbar1 |
| Strain Strategy: | T012754.Gpbar1 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | G protein-coupled bile acid receptor 1 |
| Also Known As: | BG37,GPCR,GPR131,M-BAR,TGR5 |
| NCBI Number: | 227289 |
| MGI Number: | 2653863 |
| Chromosome: | 1 |
| Deletion (size): | -6318bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,growth/size/body,immune system,nervous system,behavior/neurological,Physiological system,cardiovascular system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,Cell biology,Cell Proliferation,cellular,Organelles membrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T012754.Gpbar1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved,Live |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells. Nat Commun (2025) |
| Gene Family: | G protein-coupled bile acid receptor |