BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Klem11Cd10662/Gpt |
| Strain Number: | T011848 |
| Official Symbol: | Kl |
| Strain Strategy: | T011848.Kl Cas9-KO Strategy-EN.pdfT011848.Klotho KO strain info.pdf |
| Official Full Name: | klotho |
| Also Known As: | alpha-kl |
| NCBI Number: | 16591 |
| MGI Number: | 1101771 |
| Chromosome: | 5 |
| Deletion (size): | -10662bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,hearing/ear,behavior/neurological,Physiological system,integument,cardiovascular system,skeleton,craniofacial ,Muscle ,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,cellular,Organelles membrane,Molecular biology,Signal Transduction,hydrolytic enzyme |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T011848.Kl Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Klotho alleviates sepsis-associated myocardial inflammation and apoptosis. Eur J Pharmacol (2025) |
| Gene Family: | Glycoside hydrolase family 1 |