| Strain Name: |
C57BL/6JGpt-Padi4em6Cd1080/Gpt |
| Strain Number: |
T011513 |
| Official Symbol: |
Padi4 |
| Strain Strategy: |
T011513.Padi4 Cas9-KO Strategy-EN.pdf
|
| Official Full Name: |
peptidyl arginine deiminase, type IV |
| Also Known As: |
Pad4,Pdi4 |
| NCBI Number: |
18602
|
| MGI Number: |
1338898
|
| Chromosome: |
4 |
| Deletion (size): |
-1080bp |
| Research Areas: |
Physiological system,renal/urinary system |
| Strain Background: |
[N000013] C57BL/6JGpt |
| Modification Type: |
Knockout (KO) |
| Genotyping Protocols: |
T011513.Padi4 Genotyping Protocol(KO).pdf
|
| Inventory Status: |
Cryopreserved |
| Sale Status: |
IF (Available for Distribution) |
| Health Status: |
Specific pathogen free (SPF) |
| Health Report: |
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| Publications: |
1. Tyrosine phosphatase SHP2 exacerbates psoriasis-like skin inflammation in mice via ERK5-dependent NETosis. MedComm (2022)2. The role of protein arginine deiminase 4-dependent neutrophil extracellular traps formation in ulcerative colitis. Front Immunol (2023)3. Neutrophil autophagy induced by monosodium urate crystals facilitates neutrophil extracellular traps formation and inflammation remission in gouty arthritis. Front Endocrinol (2023)4. The scaffold of neutrophil extracellular traps promotes CCA progression and modulates angiogenesis via ITGAV/NFkappaB. Cell Commun Signal (2024)5. Increased neutrophil extracellular traps caused by diet‐induced obesity delay fracture healing. FASEB J (2024)6. Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway. Int Immunopharmacol (2024)
|
| Gene Family: |
Peptidyl arginine deiminases
|
