BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Casp6em12Cd5440/Gpt |
| Strain Number: | T006014 |
| Official Symbol: | Casp6 |
| Strain Strategy: | T006014.Casp6 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | caspase 6 |
| Also Known As: | CASP-6,Mch2 |
| NCBI Number: | 12368 |
| MGI Number: | 1312921 |
| Chromosome: | 3 |
| Deletion (size): | -5440bp |
| Research Areas: | Metabolic research,Developmental Biology,nervous system,vision/eye,Cell death,Protein metabolism,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,cell nucleus,hydrolytic enzyme |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T006014.Casp6 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Caspase-6/Gasdermin C-Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2-Dependent Recruitment of Myeloid-Derived Suppressor Cells. Adv Sci (Weinh) (2025) |
| Gene Family: | Caspases |