Cell Apoptosis Experiment

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Case: Pharmacological efficacy evaluation of ADC drug DS-8201a (targeting HER2) in vitro.



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Fig. Apoptosis induced by DS-8201a in target cells SK-BR-3 at different concentrations


GPT Advantages


  • Extensive library of target cells (300+ cancer cell lines and humanized cell lines) in certified BSL-2 level laboratories.

  • Free provision of comparator antibody therapy for common viral infections.

  • Proficiency in Flow Cytometry and molecular analysis platforms.

  • Availability of immune system humanized mice for verifying the Fc effect (ADCC, ADCP, etc.) on ADC drug antibodies, including models like NCG-IL15, NCG-IL2, and NCG-SGM3.

  • Vast project experience.

  • Compliance with regulatory requirements for new drug application submissions.

  • Strict laboratory data storage standards to ensure experiment traceability.


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