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免疫检查点人源化

品系编号

品系简称

品系类型

T051331

B6-Fcgr1/Fcgr2-4-KO/Tg(hFcγR)-V2

TransgenicTg

T054095

BALB/c-hCD137/hFcgRs-V2

TransgenicTg

T006214

B6-hFcRn

Knockin(KI),CRISPR/Cas9

T001550

BALB/c-hCD3E

TransgenicTg

T009031

BALB/c-hCD3EDG

TransgenicTg

T003095

B6-hPD1

Knockin(KI),CRISPR/Cas9

T003455

B6-hPDL1

Knockin(KI),ES

T004022

B6-hPD1/hPDL1

Knockin(KI),CRISPR/Cas9,ES

T002726

BALB/C-hPD1

Knockin(KI),CRISPR/Cas9

T003260

BALB/c-hPDL1

Knockin(KI),ES

T004025

BALB/c-hPD1/hPDL1

Knockin(KI),CRISPR/Cas9,ES

T003366

B6-hTIGIT

Knockin(KI),CRISPR/Cas9

T004024

B6-hPD1/hTIGIT

Knockin(KI),CRISPR/Cas9

T006873

B6-hPD1/hPDL1/hTIGIT

Knockin(KI),CRISPR/Cas9,ES

T003365

BALB/c-hTIGIT

Knockin(KI),CRISPR/Cas9

T004023

BALB/c-hPD1/hTIGIT

Knockin(KI),CRISPR/Cas9

T037004

BALB/c-hPD1/hPDL1/hTIGIT

Knockin(KI),ES

T003360

B6-hCD137

Knockin(KI),CRISPR/Cas9

T004082

B6-hPD1/hCD137

Knockin(KI),CRISPR/Cas9

T003359

BALB/c-hCD137

Knockin(KI),CRISPR/Cas9

T004005

BALB/c-hPD1/hCD137

Knockin(KI),CRISPR/Cas9

T007056

BALB/c-hPD1/hPDL1/hCD137

Knockin(KI),CRISPR/Cas9,ES

T002140

B6-hOX40

Knockin(KI),CRISPR/Cas9

T003532

B6-hPD1/hOX40

Knockin(KI),CRISPR/Cas9

T004421

B6-hPD1/hOX40-v2

Knockin(KI),CRISPR/Cas9

T004363

BALB/c-hOX40

Knockin(KI),CRISPR/Cas9

T003804

BALB/c-hPD1/hOX40

Knockin(KI),CRISPR/Cas9

T003362

B6-hCTLA4

Knockin(KI),CRISPR/Cas9

T003826

B6-hPD1/hCTLA4

Knockin(KI),CRISPR/Cas9

T003361

BALB/c-hCTLA4

Knockin(KI),CRISPR/Cas9

T003720

BALB/c-hPD1/hCTLA4

Knockin(KI),CRISPR/Cas9

T007058

BALB/c-hPD1/hPDL1/hCTLA4

Knockin(KI),CRISPR/Cas9,ES

T003597

B6-hLAG3

Knockin(KI),CRISPR/Cas9

T004621

B6-hPD1/hLAG3

Knockin(KI),CRISPR/Cas9

T006876

B6-hPD1/hPDL1/hLAG3

Knockin(KI),CRISPR/Cas9,ES

T004622

BALB/c-hPD1/hLAG3

Knockin(KI),CRISPR/Cas9

T037005

BALB/c-hPD1/hPDL1/hLAG3

Knockin(KI),CRISPR/Cas9,ES

T009737

B6-hPD1/hTIM3

Knockin(KI),CRISPR/Cas9

T003894

BALB/c-hTIM3

Knockin(KI),ES

T004795

BALB/c-hPD1/hTIM3

Knockin(KI),CRISPR/Cas9

T007059

BALB/c-hPD1/hPDL1/hTIM3

Knockin(KI),CRISPR/Cas9,ES

T014695

B6-hCD73

Knockin(KI),CRISPR/Cas9

T009410

B6-hPD1/hPDL1/hCD73

Knockin(KI),CRISPR/Cas9

T036652

BALB/c-hPD1/hPDL1/hCD73

Knockin(KI),CRISPR/Cas9,ES

T007666

B6-hCD47

Knockin(KI),CRISPR/Cas9

T004666

B6-hPD1/hCD47

Knockin(KI),CRISPR/Cas9

T014646

BALB/c-hCD47

Knockin(KI),CRISPR/Cas9

T005313

BALB/c-hPD1/hCD47

Knockin(KI),CRISPR/Cas9

T004615

B6-hSIRPα

Knockin(KI),CRISPR/Cas9

T006929

B6-hSIRPα/hPD1

Knockin(KI),CRISPR/Cas9

T037264

BALB/c-hCD47/hSIRPα

Knockin(KI),CRISPR/Cas9

T005314

BALB/c-hPD1/hSIRPα

Knockin(KI),CRISPR/Cas9

T006213

B6-hPD1/hCSF1R

Knockin(KI),CRISPR/Cas9

T014757

BALB/c-hVISTR

Knockin(KI),CRISPR/Cas9

T004061

BALB/c-hPD1/hGITR

Knockin(KI),CRISPR/Cas9

T004081

B6-hPD1/hBTLA

Knockin(KI),CRISPR/Cas9

T004138

BALB/c-hPD1/hBTLA

Knockin(KI),CRISPR/Cas9,ES

T006778

B6-hPD1/hCD27

Knockin(KI),ES

T004279

B6-hPD1/hCD28

Knockin(KI),CRISPR/Cas9

T054140

BALB/c-hCD24

Knockin(KI),CRISPR/Cas9

T054092

BALB/c-hCD30

Knockin(KI),CRISPR/Cas9

T054139

BALB/c-hCD33

Knockin(KI),CRISPR/Cas9

T054080

NOD-Scid-hNKp46

Knockin(KI),CRISPR/Cas9

T054081

NOD-Scid-hNKp30

Knockin(KI),CRISPR/Cas9

T054134

NOD-Scid-hNKG2ACDEF

TransgenicTg

T054277

NOD-Scid-hCS1

Knockin(KI),CRISPR/Cas9

T054275

NOD-Scid-hCD244

Knockin(KI),CRISPR/Cas9

T054276

NOD-Scid-hCD244/hCD48

Knockin(KI),CRISPR/Cas9

T054283

NCG-hTHPO

Knockin(KI),CRISPR/Cas9

T054194

NOD-Scid-hNKp80/hAICL

TransgenicTg


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